HitPredict

Interactor 1: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Interactor 2: NEDD8 (Q15843)
NEDD8 (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8) (NEDD-8) (Ubiquitin-like protein Nedd8)
Gene: NEDD8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	33665565
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006511 - ubiquitin-dependent protein catabolic process GO:0008104 - protein localization GO:0031625 - ubiquitin protein ligase binding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 81
+	Hs
		923979 SQSTM_HUMAN (1-440): 0: 760: 100.00		RS27A_HUMAN (1-77): 6.66e-37: 122: 57.14
+	Hs
		475023 SQSTM_HUMAN (1-440): 0: 760: 100.00		UBB_HUMAN (1-76): 2.4e-30: 107: 57.90
+	Hs
		924341 MIB1_HUMAN (105-233): 3.47e-43: 164: 25.19		RL40_HUMAN (1-76): 3.79e-33: 112: 57.90
+	Hs
		1079539 MIB1_HUMAN (105-233): 3.47e-43: 164: 25.19		NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00
+	Dr
		47653 A0AR23_DANRE (106-247): 5.06e-22: 100: 23.61		Q7SXA3_DANRE (1-77): 5.35e-37: 122: 57.14
+	Dr
		47648 A0AR23_DANRE (106-247): 5.06e-22: 100: 23.61		Q3B7P7_DANRE (1-76): 3.36e-33: 112: 57.90