HitPredict

Interactor 1: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Interactor 2: UBQL2 (Q9UHD9)
Ubiquilin-2 (Chap1) (DSK2 homolog) (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC-2) (Ubiquitin-like product Chap1/Dsk2)
Gene: UBQLN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	33277362, 33545068
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005776 - autophagosome GO:0005829 - cytosol GO:0006511 - ubiquitin-dependent protein catabolic process GO:0140693 - molecular condensate scaffold activity
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 624
+	Hs
		923979 SQSTM_HUMAN (1-440): 0: 760: 100.00		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27
+	Hs
		1056159 NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		924341 MIB1_HUMAN (105-233): 3.47e-43: 164: 25.19		RL40_HUMAN (33-112): 7.49e-34: 127: 30.86
+	Dr
		47648 A0AR23_DANRE (106-247): 5.06e-22: 100: 23.61		Q3B7P7_DANRE (33-112): 7.49e-34: 127: 30.86
+	Dr
		47653 A0AR23_DANRE (106-247): 5.06e-22: 100: 23.61		Q7SXA3_DANRE (33-119): 4.57e-24: 100: 27.27