HitPredict

Interactor 1: SNW1 (Q13573)
SNW domain-containing protein 1 (Nuclear protein SkiP) (Nuclear receptor coactivator NCoA-62) (Ski-interacting protein)
Gene: SNW1

Interactor 2: SYF1 (Q9HCS7)
Pre-mRNA-splicing factor SYF1 (Protein HCNP) (XPA-binding protein 2)
Gene: XAB2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.644

Property	Details
Experiments	33961781, 22365833
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0071007 - U2-type catalytic step 2 spliceosome GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 536 Hs			1 855
+	Hs
		1039828 SNW1_HUMAN (1-536): 0: 752: 100.00		CRNL1_HUMAN (166-822): 5.62e-47: 182: 14.51
+	Hs
		174866 SNW1_HUMAN (1-536): 0: 752: 100.00		OGT1_HUMAN (7-468): 1.59e-37: 154: 13.55
+	Hs
		1022275 SNW1_HUMAN (1-536): 0: 752: 100.00		CSTF3_HUMAN (11-543): 2.99e-35: 145: 13.25
+	Hs
		300132 SNW1_HUMAN (1-536): 0: 752: 100.00		PRP6_HUMAN (2-353): 4.69e-26: 117: 12.92
+	Dm
		571928 BX42_DROME (1-533): 0: 644: 60.40		CRN_DROME (473-778): 5.65e-29: 125: 15.61
+	Dm
		54159 BX42_DROME (1-533): 0: 644: 60.40		SYF1_DROME (1-255): 9.35e-16: 83.9: 13.69
+	Sc
		655748 PRP45_YEAST (115-496): 3.27e-99: 306: 26.80		SYF1_YEAST (19-733): 1.86e-87: 298: 22.31
+	Sc
		655771 PRP45_YEAST (115-496): 3.27e-99: 306: 26.80		CLF1_YEAST (3-250): 5.35e-11: 68.5: 12.06