HitPredict

Interactor 1: F8VPN7 (F8VPN7)
Dedicator of cytokinesis 9
Gene: Dock9

Interactor 2: CDC42 (P60766)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	15710388
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DHR-2_Lobe_B~Ras, DHR-2_Lobe_C~Ras, PH~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2113 Mm			1 191
+	Hs
		601431 DOCK9_HUMAN (31-2074): 0: 2958: 93.01		RHOQ_HUMAN (4-187): 7.38e-91: 266: 67.94
+	Hs
		1419478 DOCK9_HUMAN (31-2074): 0: 2958: 93.01		RHOJ_HUMAN (2-188): 2.68e-85: 252: 64.17
+	Hs
		988679 DOCK9_HUMAN (31-2074): 0: 2958: 93.01		RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31
+	Hs
		1015748 DOCK9_HUMAN (31-2074): 0: 2958: 93.01		RHOG_HUMAN (1-191): 7.33e-80: 237: 60.73
+	Hs
		955556 DOCK9_HUMAN (31-2074): 0: 2958: 93.01		CDC42_HUMAN (1-191): 9.95e-80: 237: 100.00
+	Hs
		581269 DOCK9_HUMAN (31-2074): 0: 2958: 93.01		RAC2_HUMAN (1-191): 1.01e-77: 232: 68.75
+	Hs
		953651 DOCK9_HUMAN (31-2074): 0: 2958: 93.01		RAC3_HUMAN (1-177): 7.58e-76: 227: 72.32
+	Hs
		601317 DOC11_HUMAN (31-2100): 0: 2682: 58.52		RHOQ_HUMAN (4-187): 7.38e-91: 266: 67.94
+	Mm
		59255 DOC11_MOUSE (31-2100): 0: 2706: 58.95		CDC42_MOUSE (1-191): 9.95e-80: 237: 100.00
+	Hs
		1206376 DOC11_HUMAN (31-2100): 0: 2682: 58.52		RHOJ_HUMAN (2-188): 2.68e-85: 252: 64.17
+	Hs
		988420 DOC11_HUMAN (31-2100): 0: 2682: 58.52		RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31
+	Hs
		955260 DOC11_HUMAN (31-2100): 0: 2682: 58.52		CDC42_HUMAN (1-191): 9.95e-80: 237: 100.00
+	Hs
		581092 DOC11_HUMAN (31-2100): 0: 2682: 58.52		RAC2_HUMAN (1-191): 1.01e-77: 232: 68.75
+	Hs
		953486 DOC11_HUMAN (31-2100): 0: 2682: 58.52		RAC3_HUMAN (1-177): 7.58e-76: 227: 72.32
+	Mm
		953810 DOC10_MOUSE (41-2081): 0: 2659: 52.98		CDC42_MOUSE (1-191): 9.95e-80: 237: 100.00
+	Hs
		955461 DOC10_HUMAN (41-2081): 0: 2643: 53.26		CDC42_HUMAN (1-191): 9.95e-80: 237: 100.00
+	At
		1342972 SPK1_ARATH (341-2067): 0: 1132: 20.53		RAC9_ARATH (4-191): 7.58e-77: 230: 51.81
+	Hs
		988538 DOCK8_HUMAN (306-915): 0: 658: 29.05		RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31
+	Hs
		955389 DOCK8_HUMAN (306-915): 0: 658: 29.05		CDC42_HUMAN (1-191): 9.95e-80: 237: 100.00
+	Hs
		581295 DOCK5_HUMAN (1509-2097): 2.16e-113: 403: 17.88		RAC2_HUMAN (1-191): 1.01e-77: 232: 68.75