HitPredict

Interactor 1: RHOG (P84095)
Rho-related GTP-binding protein RhoG
Gene: RHOG

Interactor 2: DOCK9 (Q9BZ29)
Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin-1) (Zizimin-1)
Gene: DOCK9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DHR-2_Lobe_B~Ras, DHR-2_Lobe_C~Ras, PH~Ras
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 2069
+	Hs
		988679 RAC1_HUMAN (1-191): 1e-80: 239: 71.88		DOCK9_HUMAN (1-2069): 0: 2503: 100.00
+	Mm
		107030 CDC42_MOUSE (1-191): 2.01e-77: 231: 60.73		F8VPN7_MOUSE (34-2068): 0: 2396: 92.97
+	Mm
		59255 CDC42_MOUSE (1-191): 2.01e-77: 231: 60.73		DOC11_MOUSE (11-2068): 0: 2206: 58.90
+	Hs
		988420 RAC1_HUMAN (1-191): 1e-80: 239: 71.88		DOC11_HUMAN (11-2068): 0: 2188: 58.38
+	Mm
		953810 CDC42_MOUSE (1-191): 2.01e-77: 231: 60.73		DOC10_MOUSE (9-2068): 0: 2193: 51.86
+	Mm
		988902 RAC1_MOUSE (1-191): 1e-80: 239: 71.88		DOCK1_MOUSE (395-1220): 0: 620: 14.22
+	Hs
		1015434 RHOG_HUMAN (1-191): 1.42e-80: 239: 100.00		DOCK1_HUMAN (395-1220): 0: 615: 13.87
+	Hs
		988363 RAC1_HUMAN (1-191): 1e-80: 239: 71.88		DOCK1_HUMAN (395-1220): 0: 615: 13.87
+	Hs
		988519 RAC1_HUMAN (1-191): 1e-80: 239: 71.88		DOCK4_HUMAN (395-1225): 4.94e-176: 590: 14.85
+	Hs
		988576 RAC1_HUMAN (1-191): 1e-80: 239: 71.88		DOCK2_HUMAN (395-1220): 4.83e-175: 585: 13.09
+	Hs
		1015791 RHOG_HUMAN (1-191): 1.42e-80: 239: 100.00		DOCK5_HUMAN (395-1224): 1.43e-163: 553: 13.46
+	Hs
		988712 RAC1_HUMAN (1-191): 1e-80: 239: 71.88		DOCK5_HUMAN (395-1224): 1.43e-163: 553: 13.46
+	Hs
		988515 RAC1_HUMAN (1-191): 1e-80: 239: 71.88		DOCK3_HUMAN (395-1225): 2.24e-145: 502: 14.53
+	Hs
		1015418 RHOG_HUMAN (1-191): 1.42e-80: 239: 100.00		GAB1_HUMAN (171-470): 6.89e-66: 240: 17.39
+	Hs
		988340 RAC1_HUMAN (1-191): 1e-80: 239: 71.88		GAB1_HUMAN (171-470): 6.89e-66: 240: 17.39
+	Hs
		988617 RAC1_HUMAN (1-191): 1e-80: 239: 71.88		DOCK7_HUMAN (11-205): 1.46e-48: 194: 24.88
+	Hs
		988608 RAC1_HUMAN (1-191): 1e-80: 239: 71.88		DOCK6_HUMAN (9-176): 1.35e-43: 177: 23.37
+	Hs
		988538 RAC1_HUMAN (1-191): 1e-80: 239: 71.88		DOCK8_HUMAN (7-167): 5.25e-42: 172: 21.23
+	Hs
		1015802 RHOG_HUMAN (1-191): 1.42e-80: 239: 100.00		PKHA1_HUMAN (149-366): 1.24e-35: 143: 18.83
+	Hs
		988724 RAC1_HUMAN (1-191): 1e-80: 239: 71.88		PKHA1_HUMAN (149-366): 1.24e-35: 143: 18.83