HitPredict

Interactor 1: UBP4 (Q13107)
Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Ubiquitous nuclear protein homolog)
Gene: USP4

Interactor 2: Q4VC15 (Q4VC15)
ubiquitinyl hydrolase 1 (EC 3.4.19.12)
Gene: USP32

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	19615732
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	UCH~UCH
Common GO terms	GO:0004843 - cysteine-type deubiquitinase activity GO:0016579 - protein deubiquitination
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 963 Hs			1 389
+	Hs
		1094588 UBP4_HUMAN (1-963): 0: 900: 100.00		UBP32_HUMAN (1-389): 4.19e-103: 335: 100.00
+	Hs
		1338649 UBP15_HUMAN (1-927): 0: 742: 57.88		UBP32_HUMAN (1-389): 4.19e-103: 335: 100.00
+	Hs
		1094615 UBP4_HUMAN (1-963): 0: 900: 100.00		UBP28_HUMAN (5-385): 1.13e-44: 167: 18.80
+	Hs
		317167 UBP4_HUMAN (1-963): 0: 900: 100.00		UBP1_HUMAN (4-351): 2.59e-41: 156: 16.62
+	Hs
		907405 UBP4_HUMAN (1-963): 0: 900: 100.00		UBP11_HUMAN (215-362): 2.64e-23: 104: 20.67
+	Hs
		322926 UBP4_HUMAN (1-963): 0: 900: 100.00		UBP19_HUMAN (163-370): 3.28e-23: 103: 15.60
+	Hs
		1094528 UBP4_HUMAN (1-963): 0: 900: 100.00		UBP4_HUMAN (150-356): 1.85e-21: 98.5: 17.23
+	Hs
		1094663 UBP4_HUMAN (1-963): 0: 900: 100.00		UBP15_HUMAN (117-374): 2.69e-20: 95: 15.83
+	Hs
		1094654 UBP4_HUMAN (1-963): 0: 900: 100.00		UBP21_HUMAN (281-350): 1.86e-15: 79.8: 32.86
+	Hs
		1402027 UBP15_HUMAN (1-927): 0: 742: 57.88		UBP28_HUMAN (5-385): 1.13e-44: 167: 18.80
+	Hs
		907638 UBP15_HUMAN (1-927): 0: 742: 57.88		UBP11_HUMAN (215-362): 2.64e-23: 104: 20.67
+	Hs
		1490806 UBP15_HUMAN (1-927): 0: 742: 57.88		UBP20_HUMAN (225-374): 4.88e-21: 97.3: 17.76
+	Hs
		1353440 UBP15_HUMAN (1-927): 0: 742: 57.88		UBP33_HUMAN (255-374): 1.25e-20: 96.2: 19.84
+	Hs
		1491395 UBP15_HUMAN (1-927): 0: 742: 57.88		UBP15_HUMAN (117-374): 2.69e-20: 95: 15.83
+	Hs
		1258111 UBP15_HUMAN (1-927): 0: 742: 57.88		UBP51_HUMAN (279-355): 1.1e-19: 92.8: 24.68
+	Mm
		1341662 UBP15_MOUSE (1-927): 0: 739: 57.46		UBP15_MOUSE (117-374): 4.36e-20: 94.3: 15.83
+	Hs
		288550 UBP15_HUMAN (1-927): 0: 742: 57.88		UBP2_HUMAN (6-96): 8.41e-18: 87.1: 34.07
+	Hs
		828266 UBP15_HUMAN (1-927): 0: 742: 57.88		UBP8_HUMAN (295-349): 1.53e-16: 83.6: 39.29
+	Hs
		1460948 UBP15_HUMAN (1-927): 0: 742: 57.88		UBP21_HUMAN (281-350): 1.86e-15: 79.8: 32.86