Interactor 1: NMDE2 (Q13224)
Glutamate receptor ionotropic, NMDA 2B (GluN2B) (Glutamate [NMDA] receptor subunit epsilon-2) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3)
Gene: GRIN2B

Interactor 2: KCC2A (Q9UQM7)
Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17)
Gene: CAMK2A

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.757

The method score is based on:

Property Details
Experiments 9694809, 11459059, 19086921, 16436603, 34667946, 21768120, 28130356, 23028764, 19453375
Identification Methods affinity chromatography technology, pull down, enzymatic study, competition binding
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0014069 - postsynaptic density
GO:0043005 - neuron projection
GO:0048168 - regulation of neuronal synaptic plasticity
GO:0060291 - long-term synaptic potentiation
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1484
Hs

1 478
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Service provided by Combinatics, Japan

Last updated: 11Aug2025