HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: IKBD (Q8NI38)
NF-kappa-B inhibitor delta (NFKB inhibitor delta) (I-kappa-B-delta) (IkB-delta) (IkappaBdelta) (IkappaBNS) (T-cell activation NFKB-like protein) (TA-NFKBH)
Gene: NFKBID

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37788672
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~Cullin
Common GO terms	GO:0005634 - nucleus GO:0006954 - inflammatory response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 768 Hs			1 313
+	Hs
		1091393 CUL3_HUMAN (1-768): 0: 943: 100.00		ANK3_HUMAN (19-313): 1.27e-65: 225: 23.03
+	Hs
		177215 CUL3_HUMAN (1-768): 0: 943: 100.00		ANR28_HUMAN (1-306): 1.6e-47: 172: 20.38
+	Hs
		1113629 CUL3_HUMAN (1-768): 0: 943: 100.00		ANKH1_HUMAN (1-232): 2.49e-40: 152: 17.69
+	Hs
		920438 CUL3_HUMAN (1-768): 0: 943: 100.00		DAPK1_HUMAN (78-308): 1.82e-34: 135: 17.17
+	Hs
		1091394 CUL4A_HUMAN (10-768): 0: 801: 38.32		ANK3_HUMAN (19-313): 1.27e-65: 225: 23.03
+	Hs
		1113716 CUL3_HUMAN (1-768): 0: 943: 100.00		ANR52_HUMAN (17-211): 7.84e-15: 77.1: 20.69
+	Hs
		626216 CUL3_HUMAN (1-768): 0: 943: 100.00		NFKB1_HUMAN (160-307): 2.11e-12: 69.8: 26.32
+	Hs
		1026717 CUL3_HUMAN (1-768): 0: 943: 100.00		NFKB2_HUMAN (183-311): 7.96e-12: 67.8: 24.81
+	Hs
		592933 CUL3_HUMAN (1-768): 0: 943: 100.00		ANK1_HUMAN (1-69): 1.62e-10: 64.2: 7.25
+	Hs
		1114526 CUL3_HUMAN (1-768): 0: 943: 100.00		ANFY1_HUMAN (85-252): 3.24e-10: 63.2: 33.70
+	Hs
		295498 CUL3_HUMAN (1-768): 0: 943: 100.00		PSD10_HUMAN (82-293): 1.11e-10: 62.4: 29.11
+	Hs
		634922 CUL4A_HUMAN (10-768): 0: 801: 38.32		BCL3_HUMAN (9-312): 4.66e-59: 197: 28.34
+	Hs
		626217 CUL4A_HUMAN (10-768): 0: 801: 38.32		NFKB1_HUMAN (160-307): 2.11e-12: 69.8: 26.32
+	Hs
		1026718 CUL4A_HUMAN (10-768): 0: 801: 38.32		NFKB2_HUMAN (183-311): 7.96e-12: 67.8: 24.81
+	Hs
		626218 CUL4B_HUMAN (5-768): 0: 796: 36.77		NFKB1_HUMAN (160-307): 2.11e-12: 69.8: 26.32
+	Hs
		1115111 CUL4A_HUMAN (10-768): 0: 801: 38.32		ANFY1_HUMAN (85-252): 3.24e-10: 63.2: 33.70
+	Hs
		1026719 CUL4B_HUMAN (5-768): 0: 796: 36.77		NFKB2_HUMAN (183-311): 7.96e-12: 67.8: 24.81
+	Hs
		943938 CUL1_HUMAN (18-768): 0: 709: 30.57		RIPK4_HUMAN (205-308): 5.49e-12: 68.4: 20.19
+	Hs
		683454 CUL1_HUMAN (18-768): 0: 709: 30.57		IKBA_HUMAN (47-228): 7.77e-11: 63.9: 30.57
+	Hs
		127783 CUL1_HUMAN (18-768): 0: 709: 30.57		IKBE_HUMAN (118-305): 9.02e-10: 61.3: 22.05