Protein: SCML1
Sex comb on midleg-like protein 1

Gene: SCML1
Organism: Homo sapiens
Interactions: 58
UniProt ID: Q9UN30

Gene Ontology (top 5):
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0042393 - histone binding
GO:0045892 - negative regulation of DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1006884

PHC1
Polyhomeotic-like protein 1

4

18

High-throughput

0.903

High

920361

PLK1
Serine/threonine-protein kinase PLK1

2

1

High-throughput

0.789

High

1312514

PHC2
Polyhomeotic-like protein 2

2

19

High-throughput

0.789

High

1336939

PHC3
Polyhomeotic-like protein 3

2

17

High-throughput

0.789

High

140484

SDCB1
Syntenin-1

2

3

High-throughput

0.783

High

1218286

SMBT2
Scm-like with four MBT domains protein 2

2

18

High-throughput

0.783

High

1348576

LNX1
E3 ubiquitin-protein ligase LNX

2

1

High-throughput

0.700

High

557524

SRC
Proto-oncogene tyrosine-protein kinase Src

1

2

High-throughput

0.691

High

1391852

AURKB
Aurora kinase B

1

1

High-throughput

0.691

High

684045

PTN3
Tyrosine-protein phosphatase non-receptor type 3

1

3

High-throughput

0.640

High

549028

KPSH1
Serine/threonine-protein kinase H1

1

1

High-throughput

0.618

High

708871

PTN4
Tyrosine-protein phosphatase non-receptor type 4

1

3

High-throughput

0.618

High

891357

GSK3A
Glycogen synthase kinase-3 alpha

1

2

High-throughput

0.618

High

891883

GSK3B
Glycogen synthase kinase-3 beta

1

3

High-throughput

0.618

High

1288394

TLK2
Serine/threonine-protein kinase tousled-like 2

1

1

High-throughput

0.618

High

339007

CBX6
Chromobox protein homolog 6

2

20

High-throughput

0.611

High

766133

PCGF2
Polycomb group RING finger protein 2

2

20

High-throughput

0.611

High

125912

ARVC
Splicing regulator ARVCF

2

2

High-throughput

0.601

High

1132246

CBX2
Chromobox protein homolog 2

2

20

High-throughput

0.584

High

1145437

RNPS1
RNA-binding protein with serine-rich domain 1

2

0

High-throughput

0.576

High

749823

CADH5
Cadherin-5

2

1

High-throughput

0.574

High

1462130

E41L3
Band 4.1-like protein 3

2

3

High-throughput

0.574

High

129826

CBX4
E3 SUMO-protein ligase CBX4

1

20

High-throughput

0.536

High

288816

NPM3
Nucleoplasmin-3

1

1

High-throughput

0.536

High

447578

NPM
Nucleophosmin

1

1

High-throughput

0.536

High

610509

PRS6A
26S proteasome regulatory subunit 6A

1

7

High-throughput

0.536

High

766003

BMI1
Polycomb complex protein BMI-1

1

20

High-throughput

0.536

High

1390754

DYL2
Dynein light chain 2, cytoplasmic

1

3

High-throughput

0.536

High

1412835

PCGF1
Polycomb group RING finger protein 1

1

20

High-throughput

0.536

High

1438668

CBX8
Chromobox protein homolog 8

1

20

High-throughput

0.536

High

1348993

ZCH10
Zinc finger CCHC domain-containing protein 10

1

1

High-throughput

0.489

High

1395092

JPH4
Junctophilin-4

1

1

High-throughput

0.489

High

1433654

E41L1
Band 4.1-like protein 1

1

4

High-throughput

0.489

High

260610

BRD4
Bromodomain-containing protein 4

1

8

High-throughput

0.479

High

342368

BRD1
Bromodomain-containing protein 1

1

5

High-throughput

0.479

High

1114649

CUL3
Cullin-3

1

3

High-throughput

0.479

High

1141362

BRD3
Bromodomain-containing protein 3

1

10

High-throughput

0.479

High

1404837

RING2
E3 ubiquitin-protein ligase RING2

1

20

High-throughput

0.479

High

1239156

NEPRO
Nucleolus and neural progenitor protein

1

0

High-throughput

0.458

High

1416419

CDAC1
Cytidine and dCMP deaminase domain-containing protein 1

1

0

High-throughput

0.458

High

1068866

IFFO1
Non-homologous end joining factor IFFO1

1

1

High-throughput

0.437

High

1200470

COBL1
Cordon-bleu protein-like 1

1

1

High-throughput

0.437

High

1290815

ZCH18
Zinc finger CCCH domain-containing protein 18

1

1

High-throughput

0.437

High

1337525

DDHD1
Phospholipase DDHD1

1

1

High-throughput

0.437

High

1419411

ACTBM
Putative beta-actin-like protein 3

1

1

High-throughput

0.437

High

1434225

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.437

High

1435260

WDR55
WD repeat-containing protein 55

1

1

High-throughput

0.437

High

1398543

CCD43
Coiled-coil domain-containing protein 43

3

0

High-throughput

0.347

High

424108

ITB2
Integrin beta-2

2

0

High-throughput

0.316

High

904479

RENBP
N-acylglucosamine 2-epimerase

2

0

High-throughput

0.316

High

375014

RASH
GTPase HRas

1

0

High-throughput

0.279

Low

725566

KAP3
cAMP-dependent protein kinase type II-beta regulatory subunit

1

0

High-throughput

0.279

Low

1339411

GP156
Probable G-protein coupled receptor 156

1

0

High-throughput

0.279

Low

1393551

MR1L1
MORF4 family-associated protein 1-like 1

1

0

High-throughput

0.279

Low

49134

BLT3B
Bridge-like lipid transfer protein family member 3B

1

0

High-throughput

0.249

Low

1314113

AMOL1
Angiomotin-like protein 1

1

0

High-throughput

0.249

Low

1462122

UTP16
U3 small nucleolar RNA-associated protein NOL7

1

0

High-throughput

0.249

Low

1395429

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025