HitPredict

Interactor 1: MYPC3 (Q14896)
Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform)
Gene: MYBPC3

Interactor 2: MYOME (Q5VU43)
Myomegalin (Cardiomyopathy-associated protein 2) (Phosphodiesterase 4D-interacting protein)
Gene: PDE4DIP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.42	0.50	0.462

Property	Details
Experiments	21569246
Identification Methods	two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1274 Hs			1 2346
+	Hs
		249150 DSCAM_HUMAN (364-1273): 2.85e-70: 262: 13.88		MYOME_HUMAN (1-2346): 0: 679: 100.00
+	Hs
		556926 MYPC3_HUMAN (1-1274): 0: 769: 100.00		MYH7_HUMAN (665-1581): 3.3e-22: 107: 13.43
+	Hs
		1125792 MYPC2_HUMAN (5-772): 3.28e-36: 151: 13.73		MYOME_HUMAN (1-2346): 0: 679: 100.00
+	Mm
		1037833 Q3UIK0_MOUSE (1-1274): 0: 748: 88.80		MYH6_MOUSE (1302-2008): 2.49e-11: 71.9: 10.14
+	Mm
		267088 MYPC3_MOUSE (1-1274): 0: 742: 88.10		LAMB1_MOUSE (342-655): 3.83e-12: 74.3: 23.55
+	Mm
		267098 MYPC3_MOUSE (1-1274): 0: 742: 88.10		MYH6_MOUSE (1302-2008): 2.49e-11: 71.9: 10.14
+	Hs
		909964 MYOM1_HUMAN (769-863): 1.83e-10: 67.8: 38.14		MYOME_HUMAN (1-2346): 0: 679: 100.00
+	Hs
		1088174 CNTN1_HUMAN (545-1266): 8.01e-39: 159: 12.00		MYH4_HUMAN (1265-2339): 3.03e-31: 137: 10.00
+	Hs
		563055 MYPC2_HUMAN (5-772): 3.28e-36: 151: 13.73		MYH8_HUMAN (1265-2328): 3.06e-32: 140: 10.80
+	Hs
		272187 OBSL1_HUMAN (396-617): 6.19e-11: 69.3: 25.52		NUMA1_HUMAN (1-1306): 3.35e-47: 189: 11.77
+	Hs
		272180 OBSL1_HUMAN (396-617): 6.19e-11: 69.3: 25.52		GOGB1_HUMAN (688-2333): 9.17e-42: 172: 11.44
+	Hs
		271983 OBSL1_HUMAN (396-617): 6.19e-11: 69.3: 25.52		CENPF_HUMAN (901-2161): 3.62e-35: 150: 9.01
+	Dm
		432213 TITIN_DROME (1109-1273): 4.52e-17: 89.9: 23.49		MYSA_DROME (29-785): 1.4e-23: 112: 11.88
+	Hs
		556906 MYOM2_HUMAN (771-1164): 8.68e-18: 91.7: 24.94		MYH7_HUMAN (665-1581): 3.3e-22: 107: 13.43
+	Mm
		1037840 Q8BUJ0_MOUSE (1064-1273): 3.27e-14: 80.1: 31.31		MYH6_MOUSE (1302-2008): 2.49e-11: 71.9: 10.14
+	Mm
		1037836 MYOM1_MOUSE (769-965): 1.75e-13: 77.8: 25.73		MYH6_MOUSE (1302-2008): 2.49e-11: 71.9: 10.14
+	Hs
		772931 TITIN_HUMAN (1-101): 2.46e-10: 67.6: 17.43		MYH9_HUMAN (1788-2316): 5.15e-13: 77.4: 12.36
+	Hs
		271833 OBSL1_HUMAN (396-617): 6.19e-11: 69.3: 25.52		LAMB1_HUMAN (342-655): 2.9e-12: 74.7: 24.86
+	Hs
		271874 OBSL1_HUMAN (396-617): 6.19e-11: 69.3: 25.52		DESP_HUMAN (6-681): 6.11e-10: 67.4: 20.72
+	Hs
		587751 TITIN_HUMAN (1-101): 2.46e-10: 67.6: 17.43		DESP_HUMAN (6-681): 6.11e-10: 67.4: 20.72