HitPredict

Interactor 1: MYPC2 (Q14324)
Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform)
Gene: MYBPC2

Interactor 2: MYOME (Q5VU43)
Myomegalin (Cardiomyopathy-associated protein 2) (Phosphodiesterase 4D-interacting protein)
Gene: PDE4DIP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.50	0.494

Property	Details
Experiments	23414517
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1141 Hs			1 2346
+	Hs
		249150 DSCAM_HUMAN (430-1140): 3.14e-44: 178: 12.60		MYOME_HUMAN (1-2346): 0: 679: 100.00
+	Hs
		563055 MYPC2_HUMAN (1-1141): 0: 696: 100.00		MYH8_HUMAN (1265-2328): 3.06e-32: 140: 10.80
+	Hs
		1133320 MYPC3_HUMAN (1-639): 8.95e-38: 156: 12.15		MYOME_HUMAN (1-2346): 0: 679: 100.00
+	Hs
		909964 MYOM1_HUMAN (636-725): 2.02e-09: 64.3: 35.87		MYOME_HUMAN (1-2346): 0: 679: 100.00
+	Hs
		1088174 CNTN1_HUMAN (3-727): 1.67e-34: 145: 9.56		MYH4_HUMAN (1265-2339): 3.03e-31: 137: 10.00
+	Hs
		556926 MYPC3_HUMAN (1-639): 8.95e-38: 156: 12.15		MYH7_HUMAN (665-1581): 3.3e-22: 107: 13.43
+	Dm
		432213 TITIN_DROME (762-1141): 6.54e-27: 121: 14.00		MYSA_DROME (29-785): 1.4e-23: 112: 11.88
+	Mm
		267088 MYPC3_MOUSE (1-639): 6.45e-37: 153: 12.89		LAMB1_MOUSE (342-655): 3.83e-12: 74.3: 23.55
+	Mm
		1037833 Q3UIK0_MOUSE (1-639): 1.45e-37: 155: 12.61		MYH6_MOUSE (1302-2008): 2.49e-11: 71.9: 10.14
+	Mm
		267098 MYPC3_MOUSE (1-639): 6.45e-37: 153: 12.89		MYH6_MOUSE (1302-2008): 2.49e-11: 71.9: 10.14
+	Hs
		271983 OBSL1_HUMAN (271-435): 2.59e-09: 63.9: 25.90		CENPF_HUMAN (901-2161): 3.62e-35: 150: 9.01
+	Hs
		556906 MYOM2_HUMAN (77-540): 1.75e-20: 100: 15.08		MYH7_HUMAN (665-1581): 3.3e-22: 107: 13.43
+	Mm
		1037840 Q8BUJ0_MOUSE (931-1140): 2.38e-16: 86.7: 33.33		MYH6_MOUSE (1302-2008): 2.49e-11: 71.9: 10.14
+	Mm
		1037836 MYOM1_MOUSE (636-914): 1.69e-15: 84.3: 25.95		MYH6_MOUSE (1302-2008): 2.49e-11: 71.9: 10.14
+	Hs
		1035528 TITIN_HUMAN (737-945): 6.08e-12: 72.9: 13.49		CENPE_HUMAN (1535-2336): 3.63e-13: 78.1: 10.44
+	Hs
		772931 TITIN_HUMAN (737-945): 6.08e-12: 72.9: 13.49		MYH9_HUMAN (1788-2316): 5.15e-13: 77.4: 12.36
+	Hs
		772822 MYLK_HUMAN (246-626): 2.96e-09: 63.9: 22.80		MYH9_HUMAN (1788-2316): 5.15e-13: 77.4: 12.36
+	Hs
		587751 TITIN_HUMAN (737-945): 6.08e-12: 72.9: 13.49		DESP_HUMAN (6-681): 6.11e-10: 67.4: 20.72
+	Hs
		271833 OBSL1_HUMAN (271-435): 2.59e-09: 63.9: 25.90		LAMB1_HUMAN (342-655): 2.9e-12: 74.7: 24.86
+	Hs
		271874 OBSL1_HUMAN (271-435): 2.59e-09: 63.9: 25.90		DESP_HUMAN (6-681): 6.11e-10: 67.4: 20.72