HitPredict

Interactor 1: RBBP5 (Q15291)
Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3)
Gene: RBBP5

Interactor 2: YETS2 (Q9ULM3)
YEATS domain-containing protein 2
Gene: YEATS2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	24981860, 37689310
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0042393 - histone binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 538 Hs			1 1422
+	Hs
		965326 WDR5_HUMAN (146-424): 6.36e-49: 173: 12.50		YETS2_HUMAN (1-1422): 0: 659: 100.00
+	Hs
		1450949 NLE1_HUMAN (2-135): 3.9e-33: 133: 18.38		YETS2_HUMAN (1-1422): 0: 659: 100.00
+	Hs
		194567 RBBP5_HUMAN (1-538): 9.43e-134: 400: 100.00		KDM6A_HUMAN (572-1224): 5.01e-50: 197: 14.92
+	Hs
		1145549 RBBP5_HUMAN (1-538): 9.43e-134: 400: 100.00		CHD7_HUMAN (259-786): 4.45e-13: 76.9: 10.24
+	Hs
		1145497 RBBP5_HUMAN (1-538): 9.43e-134: 400: 100.00		KMT2C_HUMAN (96-897): 6.92e-13: 76.2: 11.06
+	Hs
		194598 FBXW7_HUMAN (52-391): 4.03e-62: 218: 13.08		KDM6A_HUMAN (572-1224): 5.01e-50: 197: 14.92
+	Hs
		104294 WDR5_HUMAN (146-424): 6.36e-49: 173: 12.50		F5H5V6_HUMAN (592-1224): 2.61e-56: 217: 15.69
+	Hs
		194540 WDR5_HUMAN (146-424): 6.36e-49: 173: 12.50		KDM6A_HUMAN (572-1224): 5.01e-50: 197: 14.92
+	Dm
		1463914 WDS_DROME (140-422): 2.14e-48: 173: 11.32		Q9VLL1_DROME (948-1417): 3.74e-48: 189: 14.87
+	Hs
		964868 WDR5_HUMAN (146-424): 6.36e-49: 173: 12.50		ENL_HUMAN (203-536): 8.45e-43: 167: 19.38
+	Hs
		1380165 FBXW7_HUMAN (52-391): 4.03e-62: 218: 13.08		PRR36_HUMAN (79-1184): 4.25e-19: 96.2: 9.20
+	Hs
		340367 POC1A_HUMAN (145-428): 2.2e-44: 163: 10.88		YETS4_HUMAN (196-404): 3.62e-40: 150: 26.32
+	Mm
		965395 WDR5_MOUSE (146-424): 6.36e-49: 173: 12.50		KMT2C_MOUSE (367-1122): 8.44e-17: 89.1: 9.83
+	Hs
		1129735 WDR33_HUMAN (3-225): 1.03e-51: 192: 14.54		MDC1_HUMAN (746-1345): 4.43e-11: 70: 9.08
+	Hs
		965173 WDR5_HUMAN (146-424): 6.36e-49: 173: 12.50		CIC_HUMAN (353-1181): 1.29e-16: 88.5: 10.13
+	Hs
		965097 WDR5_HUMAN (146-424): 6.36e-49: 173: 12.50		KMT2C_HUMAN (96-897): 6.92e-13: 76.2: 11.06
+	Hs
		965255 WDR5_HUMAN (146-424): 6.36e-49: 173: 12.50		TENS1_HUMAN (370-1193): 1.99e-11: 71.4: 11.43
+	Hs
		1228283 NLE1_HUMAN (2-135): 3.9e-33: 133: 18.38		ARID2_HUMAN (436-1149): 3.61e-20: 99.9: 13.03
+	Hs
		1228269 SNR40_HUMAN (229-467): 4.38e-18: 87.7: 8.56		ARID2_HUMAN (436-1149): 3.61e-20: 99.9: 13.03
+	Hs
		1129693 SNR40_HUMAN (229-467): 4.38e-18: 87.7: 8.56		MDC1_HUMAN (746-1345): 4.43e-11: 70: 9.08