HitPredict

Interactor 1: CP135 (Q66GS9)
Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4)
Gene: CEP135

Interactor 2: ECT2 (Q9H8V3)
Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene)
Gene: ECT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol GO:0042803 - protein homodimerization activity
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1140 Hs			1 914
+	Hs
		728517 MYH11_HUMAN (417-1140): 5.39e-44: 177: 15.36		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		725246 MYH10_HUMAN (410-1140): 1.54e-40: 166: 13.95		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		725023 MYH9_HUMAN (2-429): 6.32e-14: 79: 11.93		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		551840 DESP_HUMAN (400-1134): 5.73e-13: 75.9: 11.86		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		1145981 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		PKHG1_HUMAN (367-887): 3.48e-78: 280: 16.79
+	Hs
		1356647 MYH13_HUMAN (1-788): 5.99e-33: 141: 10.29		PKHG1_HUMAN (367-887): 3.48e-78: 280: 16.79
+	Hs
		724913 MYH9_HUMAN (2-429): 6.32e-14: 79: 11.93		ARG28_HUMAN (216-807): 7.17e-88: 309: 12.32
+	Hs
		506606 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		BCR_HUMAN (453-641): 1.17e-14: 80.9: 27.69
+	Hs
		50564 MYH9_HUMAN (2-429): 6.32e-14: 79: 11.93		PKHG3_HUMAN (394-892): 2.49e-76: 273: 18.53
+	Hs
		724971 MYH9_HUMAN (2-429): 6.32e-14: 79: 11.93		ARHGH_HUMAN (398-726): 8.05e-68: 249: 23.82
+	Hs
		164130 GRDN_HUMAN (100-1138): 1.23e-43: 176: 11.61		ARHGA_HUMAN (436-704): 1.71e-23: 109: 29.33