HitPredict

Interactor 1: SKI2 (Q15477)
Superkiller complex protein 2 (Ski2) (EC 3.6.4.13) (Helicase-like protein) (HLP)
Gene: SKIC2

Interactor 2: EXOS4 (Q9NPD3)
Exosome complex component RRP41 (Exosome component 4) (Ribosomal RNA-processing protein 41) (p12A)
Gene: EXOSC4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	15231747
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1246 Hs			1 245
+	Hs
		838792 MTREX_HUMAN (210-1244): 0: 756: 33.62		EXOS4_HUMAN (1-245): 1.15e-89: 266: 100.00
+	Dm
		1479013 Q9Y134_DROME (179-1244): 0: 726: 33.46		Q9VK19_DROME (4-236): 1.16e-75: 230: 53.42
+	Hs
		838769 MTREX_HUMAN (210-1244): 0: 756: 33.62		EXOS8_HUMAN (1-234): 4.24e-62: 197: 18.73
+	At
		1456929 HEN2_ARATH (228-1244): 0: 680: 32.88		RRP41_ARATH (4-238): 4.52e-83: 249: 48.51
+	Hs
		838794 MTREX_HUMAN (210-1244): 0: 756: 33.62		EXOS5_HUMAN (2-239): 3.4e-52: 170: 26.25
+	Hs
		838723 MTREX_HUMAN (210-1244): 0: 756: 33.62		EXOS7_HUMAN (3-244): 6.38e-51: 169: 16.01
+	Hs
		838733 MTREX_HUMAN (210-1244): 0: 756: 33.62		EXOS6_HUMAN (6-232): 3.12e-47: 159: 29.05
+	At
		1456926 MTR4_ARATH (228-1244): 0: 660: 34.18		RRP41_ARATH (4-238): 4.52e-83: 249: 48.51
+	Dm
		1345985 Q9Y134_DROME (179-1244): 0: 726: 33.46		Q8T4A9_DROME (2-232): 2.06e-49: 168: 17.29
+	Sc
		863109 MTR4_YEAST (158-1244): 0: 685: 32.42		RRP41_YEAST (1-239): 2.43e-64: 202: 35.27
+	Dm
		1487626 Q9Y134_DROME (179-1244): 0: 726: 33.46		Q9VW53_DROME (17-243): 1.28e-46: 159: 25.00
+	Dm
		1475411 Q9Y134_DROME (179-1244): 0: 726: 33.46		Q9VGZ2_DROME (18-241): 9.55e-47: 157: 21.24
+	Sc
		864481 MTR4_YEAST (158-1244): 0: 685: 32.42		RRP46_YEAST (25-242): 9.84e-41: 140: 19.83
+	Sp
		151485 YE02_SCHPO (190-1244): 0: 626: 30.72		RRP45_SCHPO (2-243): 3.77e-49: 164: 10.47
+	Sc
		763845 SKI2_YEAST (42-1244): 0: 650: 35.53		RRP46_YEAST (25-242): 9.84e-41: 140: 19.83
+	Sp
		151633 YE02_SCHPO (190-1244): 0: 626: 30.72		MTR3_SCHPO (17-232): 1.97e-46: 156: 25.23
+	Hs
		1369397 DDX17_HUMAN (228-813): 1.3e-94: 321: 9.90		EXOS5_HUMAN (2-239): 3.4e-52: 170: 26.25
+	Mm
		108324 G3X9F7_MOUSE (301-481): 2.55e-11: 70.5: 28.57		EXOS4_MOUSE (1-245): 1.59e-89: 266: 95.92