HitPredict

Interactor 1: PGTB2 (P53611)
Geranylgeranyl transferase type-2 subunit beta (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit beta) (GGTase-II-beta) (Rab geranyl-geranyltransferase subunit beta) (Rab GG transferase beta) (Rab GGTase beta) (Rab geranylgeranyltransferase subunit beta) (Type II protein geranyl-geranyltransferase subunit beta)
Gene: RABGGTB

Interactor 2: PTAR1 (Q7Z6K3)
Protein prenyltransferase alpha subunit repeat-containing protein 1
Gene: PTAR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.80	0.808

Property	Details
Experiments	26186194, 28514442, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PPTA~Prenyltrans
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 331 Hs			1 402
+	Hs
		863114 PGTB2_HUMAN (1-331): 0: 523: 100.00		PGTA_HUMAN (51-320): 8.42e-67: 223: 19.00
+	Rn
		996050 PGTB2_RAT (1-331): 0: 516: 95.77		PGTA_RAT (51-320): 1.61e-64: 217: 18.64
+	Dm
		1376667 Q9XZ68_DROME (22-330): 3.01e-156: 442: 64.42		Q9W501_DROME (1-296): 1.04e-88: 275: 28.03
+	Dm
		1371282 Q9XZ68_DROME (22-330): 3.01e-156: 442: 64.42		Q9VN77_DROME (63-338): 1.62e-63: 214: 16.08
+	Sc
		589537 PGTB2_YEAST (17-327): 2.34e-146: 417: 51.89		PGTA_YEAST (62-336): 2.83e-61: 202: 18.46
+	Hs
		826390 FNTB_HUMAN (18-321): 4.02e-119: 351: 28.61		FNTA_HUMAN (59-320): 4.69e-56: 190: 17.42
+	Rn
		970264 FNTB_RAT (18-321): 1.05e-118: 350: 29.20		FNTA_RAT (58-320): 7.85e-55: 187: 17.74
+	Hs
		826394 PGTB1_HUMAN (18-323): 1.81e-117: 345: 28.99		FNTA_HUMAN (59-320): 4.69e-56: 190: 17.42
+	Rn
		863085 PGTB1_RAT (18-324): 3.2e-118: 347: 29.20		FNTA_RAT (58-320): 7.85e-55: 187: 17.74
+	Sp
		142884 FNTB_SCHPO (20-326): 2.87e-115: 340: 26.45		FNTA_SCHPO (57-320): 2.66e-50: 173: 15.79
+	Ce
		185232 O18197_CAEEL (13-323): 3.92e-115: 339: 30.36		O44501_CAEEL (61-335): 5.64e-50: 173: 19.64
+	Dm
		1364965 Q9VEV7_DROME (18-316): 1.24e-108: 324: 26.89		Q9VR31_DROME (59-320): 1.45e-52: 180: 16.17
+	At
		285612 PGTB1_ARATH (12-317): 7.68e-108: 321: 28.49		FNTA_ARATH (59-321): 9.94e-53: 180: 16.60
+	Sc
		602939 FNTB_YEAST (18-323): 9e-99: 299: 27.78		FNTA_YEAST (56-324): 1.81e-45: 160: 13.98
+	Sp
		223825 PGTB1_SCHPO (17-321): 2.77e-81: 252: 24.71		FNTA_SCHPO (57-320): 2.66e-50: 173: 15.79
+	Sc
		579836 PGTB1_YEAST (12-326): 2.72e-63: 207: 21.28		FNTA_YEAST (56-324): 1.81e-45: 160: 13.98
+	At
		1105141 FNTB_ARATH (97-303): 3.8e-10: 62.7: 23.50		FNTA_ARATH (59-321): 9.94e-53: 180: 16.60
+	Ce
		219506 Q19752_CAEEL (11-185): 2.31e-11: 66.2: 19.79		O44501_CAEEL (61-335): 5.64e-50: 173: 19.64