HitPredict

Interactor 1: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Interactor 2: LATS2 (Q9NRM7)
Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)
Gene: LATS2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21041410
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 1088
+	Hs
		349217 H2B1M_HUMAN (1-126): 5.4e-54: 166: 96.03		LATS1_HUMAN (1-1083): 0: 731: 49.57
+	Hs
		1144266 H2B2E_HUMAN (1-126): 6.72e-54: 166: 100.00		STK38_HUMAN (583-1065): 9.36e-148: 451: 40.58
+	Hs
		659864 H2B1O_HUMAN (1-126): 3.26e-54: 167: 99.21		AKT2_HUMAN (532-1043): 2.15e-142: 438: 23.64
+	Hs
		449682 H2B1J_HUMAN (1-126): 7.84e-54: 166: 99.21		AKT2_HUMAN (532-1043): 2.15e-142: 438: 23.64
+	Hs
		728593 H2B2E_HUMAN (1-126): 6.72e-54: 166: 100.00		AKT2_HUMAN (532-1043): 2.15e-142: 438: 23.64
+	Hs
		659863 H2B1O_HUMAN (1-126): 3.26e-54: 167: 99.21		AKT1_HUMAN (532-1043): 7.82e-142: 436: 22.16
+	Mm
		728522 H2B2B_MOUSE (1-126): 2.35e-54: 168: 97.62		AKT1_MOUSE (532-1043): 2.36e-141: 435: 22.16
+	Hs
		449681 H2B1J_HUMAN (1-126): 7.84e-54: 166: 99.21		AKT1_HUMAN (532-1043): 7.82e-142: 436: 22.16
+	Hs
		728272 H2B2E_HUMAN (1-126): 6.72e-54: 166: 100.00		AKT1_HUMAN (532-1043): 7.82e-142: 436: 22.16
+	Hs
		728056 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		AKT1_HUMAN (532-1043): 7.82e-142: 436: 22.16
+	Mm
		728524 H2B1C_MOUSE (1-126): 1.19e-53: 166: 99.21		AKT1_MOUSE (532-1043): 2.36e-141: 435: 22.16
+	Hs
		651697 H2B1H_HUMAN (1-126): 6.3e-54: 166: 98.41		KAPCB_HUMAN (638-1022): 2.4e-133: 409: 31.36
+	Hs
		651619 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		KAPCB_HUMAN (638-1022): 2.4e-133: 409: 31.36
+	Hs
		605772 H2B1H_HUMAN (1-126): 6.3e-54: 166: 98.41		KAPCA_HUMAN (633-1025): 3.08e-132: 406: 31.23
+	Hs
		659874 H2B1O_HUMAN (1-126): 3.26e-54: 167: 99.21		KS6A3_HUMAN (519-990): 6.36e-81: 282: 19.63
+	Hs
		449691 H2B1J_HUMAN (1-126): 7.84e-54: 166: 99.21		KS6A3_HUMAN (519-990): 6.36e-81: 282: 19.63
+	Hs
		908123 H2B2E_HUMAN (1-126): 6.72e-54: 166: 100.00		KS6A3_HUMAN (519-990): 6.36e-81: 282: 19.63
+	Hs
		1208915 H2B2F_HUMAN (1-126): 2.35e-54: 168: 97.62		MRCKB_HUMAN (658-1007): 1.11e-70: 261: 40.34
+	Hs
		1372353 H2B1H_HUMAN (1-126): 6.3e-54: 166: 98.41		MRCKB_HUMAN (658-1007): 1.11e-70: 261: 40.34
+	Hs
		270814 H2B2E_HUMAN (1-126): 6.72e-54: 166: 100.00		ROCK2_HUMAN (640-1008): 6.35e-67: 248: 36.90