Interactor 1: I6L996 (I6L996)
Focal adhesion kinase-related nonkinase (p125FAK)
Gene: PTK2
Interactor 2: SOCS3 (O14543)
Suppressor of cytokine signaling 3 (SOCS-3) (Cytokine-inducible SH2 protein 3) (CIS-3) (STAT-induced STAT inhibitor 3) (SSI-3)
Gene: SOCS3
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 0.80 | 0.594 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25416956 |
| Identification Methods | two hybrid prey pooling approach, two hybrid array, validated two hybrid |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PK_Tyr_Ser-Thr~SH2 |
| Common GO terms | - |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
