HitPredict

Interactor 1: SH21C (Q45HK4)
SH2 domain-containing protein 1B2 (EAT-2-related transducer) (ERT) (EAT-2B)
Gene: Sh2d1b2

Interactor 2: SLAF1 (Q9QUM4)
Signaling lymphocytic activation molecule (SLAM family member 1) (CD antigen CD150)
Gene: Slamf1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16425036
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002250 - adaptive immune response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 132 Mm			1 343
+	Mm
		204679 SH21B_MOUSE (1-132): 1.77e-41: 135: 84.09		SLAF1_MOUSE (1-343): 1.66e-91: 278: 100.00
+	Mm
		1135290 Q149T1_MOUSE (1-132): 4.44e-41: 134: 83.33		SLAF1_MOUSE (1-343): 1.66e-91: 278: 100.00
+	Mm
		813534 FYN_MOUSE (4-127): 6.92e-37: 133: 26.15		SLAF1_MOUSE (1-343): 1.66e-91: 278: 100.00
+	Mm
		1424431 SHIP1_MOUSE (4-132): 9.95e-35: 128: 30.23		SLAF1_MOUSE (1-343): 1.66e-91: 278: 100.00
+	Hs
		440537 FYN_HUMAN (4-127): 7.58e-37: 133: 26.15		SLAF1_HUMAN (1-343): 2.33e-80: 250: 59.77
+	Hs
		164857 SH21B_HUMAN (1-132): 2.61e-40: 132: 65.91		SLAF1_HUMAN (1-343): 2.33e-80: 250: 59.77
+	Hs
		1101292 SHIP1_HUMAN (5-132): 8.86e-35: 128: 28.91		SLAF1_HUMAN (1-343): 2.33e-80: 250: 59.77
+	Hs
		164869 SH21B_HUMAN (1-132): 2.61e-40: 132: 65.91		SLAF6_HUMAN (13-338): 3.25e-63: 205: 19.35
+	Mm
		1060054 Q149T1_MOUSE (1-132): 4.44e-41: 134: 83.33		CD244_MOUSE (31-329): 3.39e-61: 202: 23.53
+	Hs
		440719 FYN_HUMAN (4-127): 7.58e-37: 133: 26.15		CD244_HUMAN (39-339): 6.37e-60: 198: 21.68
+	Hs
		164873 SH21B_HUMAN (1-132): 2.61e-40: 132: 65.91		CD244_HUMAN (39-339): 6.37e-60: 198: 21.68
+	Hs
		1369278 SHIP1_HUMAN (5-132): 8.86e-35: 128: 28.91		CD244_HUMAN (39-339): 6.37e-60: 198: 21.68
+	Hs
		834227 CSK_HUMAN (3-100): 1.44e-35: 128: 30.61		CD244_HUMAN (39-339): 6.37e-60: 198: 21.68
+	Mm
		204678 SH21B_MOUSE (1-132): 1.77e-41: 135: 84.09		SLAF7_MOUSE (12-342): 1.11e-50: 173: 18.45
+	Hs
		164874 SH21B_HUMAN (1-132): 2.61e-40: 132: 65.91		SLAF7_HUMAN (5-342): 4.07e-49: 169: 17.78
+	Hs
		164875 SH21B_HUMAN (1-132): 2.61e-40: 132: 65.91		SLAF5_HUMAN (7-342): 2.48e-48: 167: 19.77
+	Hs
		840990 ABL2_HUMAN (5-126): 3.11e-35: 130: 27.05		SLAF5_HUMAN (7-342): 2.48e-48: 167: 19.77
+	Hs
		440293 FYN_HUMAN (4-127): 7.58e-37: 133: 26.15		CD2_HUMAN (10-323): 5.87e-18: 85.4: 18.83
+	Hs
		463053 YES_HUMAN (4-127): 1.3e-36: 132: 23.85		CXAR_HUMAN (7-300): 1.22e-15: 78.8: 14.05
+	Hs
		164877 SH21B_HUMAN (1-132): 2.61e-40: 132: 65.91		ROBO1_HUMAN (23-177): 5.17e-13: 72.2: 10.35