HitPredict

Interactor 1: CD244 (Q07763)
Natural killer cell receptor 2B4 (NK cell type I receptor protein 2B4) (NKR2B4) (Non-MHC restricted killing associated) (SLAM family member 4) (SLAMF4) (Signaling lymphocytic activation molecule 4) (CD antigen CD244)
Gene: CD244

Interactor 2: Q149T1 (Q149T1)
SH2 domain containing 1B1 (SH2 domain protein 1B1)
Gene: Sh2d1b1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	11689425
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002250 - adaptive immune response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 397 Mm			1 132
+	Hs
		258613 CD244_HUMAN (1-397): 6.24e-89: 275: 46.42		SH21A_HUMAN (6-105): 2.31e-44: 142: 39.00
+	Hs
		164873 CD244_HUMAN (1-397): 6.24e-89: 275: 46.42		SH21B_HUMAN (1-132): 7.32e-42: 136: 65.15
+	Hs
		557456 CD244_HUMAN (1-397): 6.24e-89: 275: 46.42		SRC_HUMAN (3-118): 4.51e-35: 128: 33.33
+	Hs
		1369278 CD244_HUMAN (1-397): 6.24e-89: 275: 46.42		SHIP1_HUMAN (4-123): 3.44e-34: 126: 31.67
+	Hs
		440719 CD244_HUMAN (1-397): 6.24e-89: 275: 46.42		FYN_HUMAN (3-118): 1.88e-34: 126: 28.57
+	Hs
		834227 CD244_HUMAN (1-397): 6.24e-89: 275: 46.42		CSK_HUMAN (3-123): 1.43e-33: 123: 29.84
+	Hs
		187404 CD244_HUMAN (1-397): 6.24e-89: 275: 46.42		SHIP2_HUMAN (5-102): 1.63e-32: 122: 41.84
+	Hs
		987921 CD244_HUMAN (1-397): 6.24e-89: 275: 46.42		GRB2_HUMAN (4-127): 1.25e-33: 118: 24.11
+	Hs
		258619 SLAF5_HUMAN (2-372): 5.16e-63: 207: 17.80		SH21A_HUMAN (6-105): 2.31e-44: 142: 39.00
+	Hs
		164875 SLAF5_HUMAN (2-372): 5.16e-63: 207: 17.80		SH21B_HUMAN (1-132): 7.32e-42: 136: 65.15
+	Mm
		1135290 SLAF1_MOUSE (54-333): 8.69e-57: 191: 19.11		Q149T1_MOUSE (1-132): 4.36e-45: 145: 100.00
+	Mm
		313108 SLAF1_MOUSE (54-333): 8.69e-57: 191: 19.11		SH21A_MOUSE (6-105): 2.6e-45: 145: 39.00
+	Mm
		204679 SLAF1_MOUSE (54-333): 8.69e-57: 191: 19.11		SH21B_MOUSE (1-132): 6.91e-45: 144: 98.49
+	Mm
		1192885 SLAF1_MOUSE (54-333): 8.69e-57: 191: 19.11		SH21C_MOUSE (1-132): 2.27e-44: 143: 83.33
+	Hs
		840990 SLAF5_HUMAN (2-372): 5.16e-63: 207: 17.80		ABL2_HUMAN (5-126): 5.81e-34: 126: 29.37
+	Hs
		258616 SLAF7_HUMAN (1-332): 1.7e-53: 182: 14.58		SH21A_HUMAN (6-105): 2.31e-44: 142: 39.00
+	Mm
		1424431 SLAF1_MOUSE (54-333): 8.69e-57: 191: 19.11		SHIP1_MOUSE (5-102): 4.89e-36: 132: 38.78
+	Hs
		164874 SLAF7_HUMAN (1-332): 1.7e-53: 182: 14.58		SH21B_HUMAN (1-132): 7.32e-42: 136: 65.15
+	Mm
		813534 SLAF1_MOUSE (54-333): 8.69e-57: 191: 19.11		FYN_MOUSE (3-118): 1.74e-34: 126: 28.57
+	Hs
		557335 CEA21_HUMAN (4-275): 5e-55: 185: 17.90		SRC_HUMAN (3-118): 4.51e-35: 128: 33.33