HitPredict

Interactor 1: KBTB6 (Q86V97)
Kelch repeat and BTB domain-containing protein 6
Gene: KBTBD6

Interactor 2: GBRL1 (Q9H0R8)
Gamma-aminobutyric acid receptor-associated protein-like 1 (Early estrogen-regulated protein) (GABA(A) receptor-associated protein-like 1) (Glandular epithelial cell protein 1) (GEC-1)
Gene: GABARAPL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.855

Property	Details
Experiments	25684205, 20562859
Identification Methods	affinity chromatography technology, x-ray crystallography, pull down, unspecified method, anti tag coimmunoprecipitation
Interaction Type	physical association, association, direct interaction

Property	Details
Interacting Pfam domains	ATG8~KBTB_W-LIR
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 674 Hs			1 117
+	Hs
		891243 KBTB7_HUMAN (1-674): 1.98e-165: 492: 89.76		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		1262066 KBTB7_HUMAN (1-674): 1.98e-165: 492: 89.76		GBRL1_HUMAN (1-117): 4.54e-56: 171: 100.00
+	Hs
		306250 KBTB7_HUMAN (1-674): 1.98e-165: 492: 89.76		GBRAP_HUMAN (1-116): 2.96e-56: 171: 87.07
+	Hs
		891206 KBTB6_HUMAN (1-674): 1.29e-159: 477: 100.00		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		306221 KBTB6_HUMAN (1-674): 1.29e-159: 477: 100.00		GBRAP_HUMAN (1-116): 2.96e-56: 171: 87.07
+	Hs
		1262059 KBTB7_HUMAN (1-674): 1.98e-165: 492: 89.76		MLP3C_HUMAN (5-116): 1.61e-44: 143: 39.47
+	Hs
		1262064 KBTB7_HUMAN (1-674): 1.98e-165: 492: 89.76		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Hs
		1201299 KBTB6_HUMAN (1-674): 1.29e-159: 477: 100.00		MLP3C_HUMAN (5-116): 1.61e-44: 143: 39.47
+	Hs
		1201302 KBTB6_HUMAN (1-674): 1.29e-159: 477: 100.00		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Hs
		891139 KEAP1_HUMAN (433-671): 3.47e-51: 189: 15.95		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		1049326 KEAP1_HUMAN (433-671): 3.47e-51: 189: 15.95		GBRL1_HUMAN (1-117): 4.54e-56: 171: 100.00
+	Hs
		306167 KEAP1_HUMAN (433-671): 3.47e-51: 189: 15.95		GBRAP_HUMAN (1-116): 2.96e-56: 171: 87.07
+	Dm
		1181841 Q7KSF5_DROME (435-671): 1.88e-44: 172: 13.73		Q9W2S2_DROME (1-116): 1.56e-57: 175: 85.35
+	Hs
		1049329 KEAP1_HUMAN (433-671): 3.47e-51: 189: 15.95		MLP3A_HUMAN (5-116): 1.09e-44: 142: 34.21
+	Hs
		1049322 KEAP1_HUMAN (433-671): 3.47e-51: 189: 15.95		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Hs
		891272 KLHL5_HUMAN (312-483): 4.15e-26: 116: 17.51		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		1299556 KLHL5_HUMAN (312-483): 4.15e-26: 116: 17.51		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Hs
		1120814 KLH12_HUMAN (505-667): 2.1e-22: 103: 13.30		MLP3A_HUMAN (5-116): 1.09e-44: 142: 34.21
+	Hs
		1120811 KLH12_HUMAN (505-667): 2.1e-22: 103: 13.30		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62