HitPredict

Interactor 1: MYOME (Q5VU43)
Myomegalin (Cardiomyopathy-associated protein 2) (Phosphodiesterase 4D-interacting protein)
Gene: PDE4DIP

Interactor 2: CC146 (Q8IYE0)
Coiled-coil domain-containing protein 146
Gene: CCDC146

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.654

Property	Details
Experiments	25416956, 32296183, unassigned1304
Identification Methods	two hybrid, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 2346 Hs			1 955
+	Mm
		878603 MYOME_MOUSE (1-2346): 1.06e-159: 550: 66.87		CTRO_MOUSE (12-492): 4.92e-14: 79.3: 11.45
+	Hs
		773186 NUMA1_HUMAN (1-1306): 3.35e-47: 189: 11.77		MYH10_HUMAN (140-941): 4.98e-45: 179: 9.65
+	Hs
		556973 MYH4_HUMAN (1265-2339): 3.03e-31: 137: 10.00		MYH7_HUMAN (91-955): 1.08e-45: 181: 12.21
+	Mm
		563088 MYH8_MOUSE (1279-2339): 5.87e-33: 143: 9.72		MYH6_MOUSE (1-825): 2.03e-39: 161: 10.91
+	Hs
		563078 MYH8_HUMAN (1265-2328): 3.06e-32: 140: 10.80		MYH13_HUMAN (223-954): 1.24e-39: 162: 11.56
+	Hs
		562992 MYH6_HUMAN (1279-2312): 4.48e-30: 133: 9.72		MYH6_HUMAN (223-954): 1.15e-40: 165: 12.58
+	Rn
		386940 MYH6_RAT (1410-2327): 4.09e-28: 127: 9.08		MYH6_RAT (73-954): 7.12e-42: 169: 10.10
+	Mm
		1037835 MYH1_MOUSE (1-829): 8.65e-30: 132: 9.93		MYH6_MOUSE (1-825): 2.03e-39: 161: 10.91
+	Hs
		157390 NUMA1_HUMAN (1-1306): 3.35e-47: 189: 11.77		CTRO_HUMAN (278-871): 3.2e-17: 89.7: 12.52
+	Hs
		1132275 GOGB1_HUMAN (688-2333): 9.17e-42: 172: 11.44		CP135_HUMAN (145-911): 1.6e-17: 90: 11.89
+	Hs
		535958 MYH4_HUMAN (1265-2339): 3.03e-31: 137: 10.00		MYH3_HUMAN (1-660): 5.85e-27: 121: 10.10
+	Hs
		563081 MYH8_HUMAN (1265-2328): 3.06e-32: 140: 10.80		MYH4_HUMAN (384-954): 3.62e-25: 115: 8.22
+	Hs
		535921 MYH6_HUMAN (1279-2312): 4.48e-30: 133: 9.72		MYH3_HUMAN (1-660): 5.85e-27: 121: 10.10
+	Zm
		5583 A0A1D6DZK4_MAIZE (1482-2333): 2.42e-24: 114: 10.33		A0A1D6DZK4_MAIZE (1-773): 1.95e-30: 132: 11.37
+	Hs
		157094 CENPF_HUMAN (901-2161): 3.62e-35: 150: 9.01		CTRO_HUMAN (278-871): 3.2e-17: 89.7: 12.52
+	Dm
		1404006 MYSN_DROME (403-1455): 2.68e-32: 140: 12.23		MYSN_DROME (423-919): 3.57e-16: 85.9: 9.88
+	Dm
		432158 MYSA_DROME (29-785): 1.4e-23: 112: 11.88		MYSA_DROME (378-954): 1.29e-23: 110: 10.26
+	Hs
		177001 CE290_HUMAN (874-2329): 3.16e-28: 127: 9.32		CP135_HUMAN (145-911): 1.6e-17: 90: 11.89
+	Hs
		157026 MYH11_HUMAN (1076-2063): 3.53e-22: 107: 11.23		CTRO_HUMAN (278-871): 3.2e-17: 89.7: 12.52