Interactor 1: ARHGG (Q5VV41)
Rho guanine nucleotide exchange factor 16 (Ephexin-4)
Gene: ARHGEF16
Interactor 2: FGD6 (Q6ZV73)
FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24)
Gene: FGD6
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.54 | 1.00 | 0.737 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32203420, unassigned2213 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PH~PH, PH~RhoGEF, RhoGEF~RhoGEF, PH~SH3_1, RhoGEF~SH3_1 |
| Common GO terms | GO:0005085 - guanyl-nucleotide exchange factor activity GO:0031267 - small GTPase binding |
| Homologous interactions | 15 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
