HitPredict

Interactor 1: SRC8 (Q60598)
Src substrate cortactin
Gene: Cttn

Interactor 2: WIPF1 (Q8K1I7)
WAS/WASL-interacting protein family member 1 (Wiskott-Aldrich syndrome protein-interacting protein) (WASP-interacting protein)
Gene: WIPF1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	12620186
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001726 - ruffle GO:0005884 - actin filament
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 546 Mm			1 493
+	Hs
		219553 SRC8_HUMAN (1-546): 5.76e-164: 479: 92.18		WIPF1_HUMAN (1-493): 1.14e-26: 114: 84.72
+	Hs
		219545 HCLS1_HUMAN (1-546): 6.71e-117: 356: 38.39		WIPF1_HUMAN (1-493): 1.14e-26: 114: 84.72
+	Hs
		571698 HCLS1_HUMAN (1-546): 6.71e-117: 356: 38.39		PCLO_HUMAN (33-457): 2.7e-09: 62.2: 12.00
+	Hs
		1353775 PACN2_HUMAN (169-546): 2.08e-40: 154: 14.17		WIPF2_HUMAN (14-493): 5.67e-27: 114: 36.18
+	Hs
		219567 PACN2_HUMAN (169-546): 2.08e-40: 154: 14.17		WIPF1_HUMAN (1-493): 1.14e-26: 114: 84.72
+	Hs
		1060681 NOSTN_HUMAN (105-545): 1.29e-41: 158: 13.19		SOS1_HUMAN (135-462): 8.61e-21: 98.3: 17.51
+	Hs
		1353774 ITSN2_HUMAN (31-545): 2.65e-31: 131: 13.73		WIPF2_HUMAN (14-493): 5.67e-27: 114: 36.18
+	Hs
		219565 ITSN2_HUMAN (31-545): 2.65e-31: 131: 13.73		WIPF1_HUMAN (1-493): 1.14e-26: 114: 84.72
+	Hs
		1060676 SPTN1_HUMAN (141-545): 3.52e-35: 143: 14.03		SOS1_HUMAN (135-462): 8.61e-21: 98.3: 17.51
+	Hs
		635521 NEBU_HUMAN (218-545): 6.61e-34: 139: 18.86		SOS1_HUMAN (135-462): 8.61e-21: 98.3: 17.51
+	Hs
		1060697 ITSN2_HUMAN (31-545): 2.65e-31: 131: 13.73		SOS1_HUMAN (135-462): 8.61e-21: 98.3: 17.51
+	Hs
		215920 MYO1E_HUMAN (175-545): 2.46e-42: 164: 14.53		SYNJ1_HUMAN (252-493): 5.04e-10: 64.5: 20.40
+	Hs
		215960 PACN2_HUMAN (169-546): 2.08e-40: 154: 14.17		SYNJ1_HUMAN (252-493): 5.04e-10: 64.5: 20.40
+	Hs
		299586 ITSN2_HUMAN (31-545): 2.65e-31: 131: 13.73		TRIO_HUMAN (245-438): 1.62e-14: 78.6: 25.91
+	Hs
		1117543 SPTN1_HUMAN (141-545): 3.52e-35: 143: 14.03		PCLO_HUMAN (33-457): 2.7e-09: 62.2: 12.00
+	Hs
		635544 NEBU_HUMAN (218-545): 6.61e-34: 139: 18.86		TITIN_HUMAN (143-349): 5.31e-09: 61.3: 19.71
+	Hs
		176277 ITSN2_HUMAN (31-545): 2.65e-31: 131: 13.73		SYNJ2_HUMAN (5-406): 4.57e-10: 64.4: 15.64
+	Ce
		73269 SH3GH_CAEEL (213-545): 4.88e-33: 132: 16.43		G5EBN5_CAEEL (63-487): 3.15e-09: 61.7: 17.81
+	Rn
		204410 SH3G2_RAT (359-545): 8.74e-29: 119: 22.17		SYNJ1_RAT (145-493): 6.17e-11: 67.2: 13.46
+	Mm
		92772 SH3G2_MOUSE (359-545): 6.73e-29: 119: 22.68		D3Z656_MOUSE (145-493): 6.3e-11: 67.2: 14.09