HitPredict

Interactor 1: NEBU (P20929)
Nebulin
Gene: NEB

Interactor 2: SOS1 (Q07889)
Son of sevenless homolog 1 (SOS-1)
Gene: SOS1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.51	0.60	0.554

Property	Details
Experiments	12482578
Identification Methods	classical fluorescence spectroscopy, circular dichroism, nuclear magnetic resonance
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 8525 Hs			1 1333
+	Hs
		1060694 PACN1_HUMAN (8092-8525): 5.95e-65: 232: 15.91		SOS1_HUMAN (1-1333): 0: 1000: 100.00
+	Hs
		1060676 SPTN1_HUMAN (7876-8525): 2.02e-58: 229: 11.33		SOS1_HUMAN (1-1333): 0: 1000: 100.00
+	Hs
		1060697 ITSN2_HUMAN (7807-8525): 4.4e-55: 217: 9.77		SOS1_HUMAN (1-1333): 0: 1000: 100.00
+	Hs
		1060703 PACN3_HUMAN (8077-8525): 1.03e-57: 210: 11.84		SOS1_HUMAN (1-1333): 0: 1000: 100.00
+	Hs
		1060677 ITSN1_HUMAN (7577-8524): 1.09e-46: 190: 11.23		SOS1_HUMAN (1-1333): 0: 1000: 100.00
+	Rn
		93231 PACN1_RAT (8077-8525): 1.09e-55: 205: 15.79		D4A3T0_RAT (1-1333): 0: 966: 96.40
+	Hs
		1060693 SRBS1_HUMAN (8368-8525): 5.43e-27: 125: 20.23		SOS1_HUMAN (1-1333): 0: 1000: 100.00
+	Hs
		1060722 ITSN2_HUMAN (7807-8525): 4.4e-55: 217: 9.77		SOS2_HUMAN (1-1131): 0: 858: 73.59
+	Hs
		1060724 PACN3_HUMAN (8077-8525): 1.03e-57: 210: 11.84		SOS2_HUMAN (1-1131): 0: 858: 73.59
+	Hs
		1060709 ITSN1_HUMAN (7577-8524): 1.09e-46: 190: 11.23		SOS2_HUMAN (1-1131): 0: 858: 73.59
+	Hs
		238815 SPTN1_HUMAN (7876-8525): 2.02e-58: 229: 11.33		KALRN_HUMAN (8-624): 5.23e-69: 259: 12.70
+	Hs
		1154138 ITSN1_HUMAN (7577-8524): 1.09e-46: 190: 11.23		PREX1_HUMAN (168-685): 3.74e-81: 296: 15.90
+	Mm
		60053 B9EKJ1_MOUSE (7538-8525): 3.02e-57: 225: 10.74		KALRN_MOUSE (8-624): 5.23e-68: 255: 12.88
+	Mm
		60071 SPTN1_MOUSE (7538-8525): 3.78e-57: 225: 10.74		KALRN_MOUSE (8-624): 5.23e-68: 255: 12.88
+	Hs
		299586 ITSN2_HUMAN (7807-8525): 4.4e-55: 217: 9.77		TRIO_HUMAN (121-694): 3.12e-61: 234: 12.54
+	Hs
		326864 RIMB1_HUMAN (8322-8525): 8.64e-10: 68.9: 15.96		RPGF4_HUMAN (518-1021): 2.05e-86: 306: 17.57
+	Mm
		60098 SRBS1_MOUSE (8246-8525): 6.02e-23: 111: 14.24		KALRN_MOUSE (8-624): 5.23e-68: 255: 12.88
+	Hs
		1293239 SH3R3_HUMAN (8343-8525): 1.76e-15: 87: 18.62		RGPS2_HUMAN (774-1023): 3.31e-23: 107: 27.34