HitPredict

Interactor 1: WDFY3 (Q8IZQ1)
WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy)
Gene: WDFY3

Interactor 2: DC2I1 (Q8WVS4)
Cytoplasmic dynein 2 intermediate chain 1 (Dynein 2 intermediate chain 1) (WD repeat-containing protein 60)
Gene: DYNC2I1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 3526 Hs			1 1066
+	Mm
		88387 E9PV60_MOUSE (1942-3275): 0: 1069: 35.40		D3Z0M9_MOUSE (10-372): 2.84e-12: 73.1: 13.99
+	Hs
		1305668 LYST_HUMAN (2060-3292): 0: 886: 23.13		MYH13_HUMAN (2-608): 6.2e-37: 154: 9.69
+	Hs
		1033325 RUFY1_HUMAN (3273-3521): 1.93e-30: 133: 23.26		DC1I2_HUMAN (382-1056): 3.33e-166: 505: 16.71
+	Hs
		903218 WDR5_HUMAN (2952-3290): 6.23e-71: 244: 15.32		EIF3A_HUMAN (6-577): 6.47e-31: 134: 11.34
+	Hs
		551655 WDR5_HUMAN (2952-3290): 6.23e-71: 244: 15.32		DESP_HUMAN (1-554): 5.69e-14: 79.3: 12.35
+	Hs
		903375 WDR5_HUMAN (2952-3290): 6.23e-71: 244: 15.32		BD1L1_HUMAN (23-488): 4.25e-13: 76.5: 12.53
+	Hs
		551766 WDR5B_HUMAN (2948-3292): 2.84e-69: 239: 16.57		DESP_HUMAN (1-554): 5.69e-14: 79.3: 12.35
+	Hs
		1040940 MTMR3_HUMAN (3275-3521): 1.52e-39: 164: 20.00		THOC2_HUMAN (10-404): 3.64e-10: 66.5: 14.15