Protein: CD33
Myeloid cell surface antigen CD33 (Sialic acid-binding Ig-like lectin 3) (Siglec-3) (gp67) (CD antigen CD33)

Gene: CD33
Organism: Homo sapiens
Interactions: 52
UniProt ID: P20138

Gene Ontology (top 5):
GO:0002765 - immune response-inhibiting signal transduction
GO:0005777 - peroxisome
GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane
GO:0007155 - cell adhesion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

335536

BMP10
Bone morphogenetic protein 10

2

1

High-throughput

0.783

High

628382

THS7A
Thrombospondin type-1 domain-containing protein 7A [Cleaved into: Thrombospondin type-1 domain-containing protein 7A, soluble form]

2

7

High-throughput

0.783

High

628355

CXCL9
C-X-C motif chemokine 9

2

0

High-throughput

0.742

High

628344

PTN6
Tyrosine-protein phosphatase non-receptor type 6

5

20

Small-scale

0.724

High

208961

CYB5B
Cytochrome b5 type B

2

1

High-throughput

0.700

High

628366

S39AB
Zinc transporter ZIP11

4

3

High-throughput

0.691

High

628345

PEX19
Peroxisomal biogenesis factor 19

4

0

High-throughput

0.661

High

628383

UBIA1
UbiA prenyltransferase domain-containing protein 1

2

0

High-throughput

0.655

High

628353

TNNC1
Troponin C, slow skeletal and cardiac muscles

2

0

High-throughput

0.649

High

628354

PTN11
Tyrosine-protein phosphatase non-receptor type 11

4

20

Small-scale

0.646

High

252275

TLR5
Toll-like receptor 5

1

20

Small-scale

0.618

High

618968

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

4

Small-scale

0.618

High

628342

CD22
B-cell receptor CD22

1

18

Small-scale

0.618

High

628376

TLR10
Toll-like receptor 10

1

20

Small-scale

0.618

High

628358

K1H1
Keratin, type I cuticular Ha1

3

4

High-throughput

0.616

High

628361

TTMP
TPA-induced transmembrane protein

2

1

High-throughput

0.606

High

628370

LFG3
Protein lifeguard 3

2

2

High-throughput

0.606

High

628348

KSYK
Tyrosine-protein kinase SYK

2

20

Small-scale

0.584

High

628380

TM100
Transmembrane protein 100

2

0

High-throughput

0.580

High

144403

SCD
Stearoyl-CoA desaturase

2

1

High-throughput

0.553

High

628351

EMD
Emerin

2

1

High-throughput

0.553

High

628369

KRT35
Keratin, type I cuticular Ha5

2

4

High-throughput

0.553

High

628350

CXCR3
C-X-C chemokine receptor type 3

1

0

High-throughput

0.546

High

628363

K1C40
Keratin, type I cytoskeletal 40

1

4

High-throughput

0.523

High

628371

SAAL1
Protein SAAL1

2

1

High-throughput

0.521

High

444899

S10A9
Protein S100-A9

1

4

Small-scale

0.515

High

628343

CBL
E3 ubiquitin-protein ligase CBL

1

5

Small-scale

0.515

High

628360

KLH22
Kelch-like protein 22

1

3

High-throughput

0.514

High

628364

WDR74
WD repeat-containing protein 74

1

2

High-throughput

0.514

High

628357

HERC3
Probable E3 ubiquitin-protein ligase HERC3

1

3

High-throughput

0.494

High

628346

LEP
Leptin

1

2

Small-scale

0.481

High

253002

LMX1B
LIM homeobox transcription factor 1-beta

1

0

High-throughput

0.481

High

628374

NUP85
Nuclear pore complex protein Nup85

1

0

High-throughput

0.481

High

557081

SRC
Proto-oncogene tyrosine-protein kinase Src

1

11

Small-scale

0.479

High

628347

ZAP70
Tyrosine-protein kinase ZAP-70

1

19

Small-scale

0.479

High

628356

CBLB
E3 ubiquitin-protein ligase CBL-B

1

4

Small-scale

0.479

High

628352

BI1
Bax inhibitor 1

1

2

High-throughput

0.445

High

628367

TB22A
TBC1 domain family member 22A

1

2

High-throughput

0.445

High

155907

SOCS3
Suppressor of cytokine signaling 3

1

17

Small-scale

0.437

High

628349

CRKL
Crk-like protein

1

8

Small-scale

0.437

High

628359

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.426

High

243888

JIP4
C-Jun-amino-terminal kinase-interacting protein 4

1

2

High-throughput

0.407

High

628365

UBR3
E3 ubiquitin-protein ligase UBR3

1

1

High-throughput

0.407

High

628378

AT131
Endoplasmic reticulum transmembrane helix translocase

1

2

High-throughput

0.407

High

628381

COMD3
COMM domain-containing protein 3

4

0

High-throughput

0.360

High

628372

GIMA5
GTPase IMAP family member 5

2

0

High-throughput

0.316

High

628373

TM243
Transmembrane protein 243

2

0

High-throughput

0.316

High

628377

TNMD
Tenomodulin

2

0

High-throughput

0.316

High

628379

RPRM
Protein reprimo

2

0

High-throughput

0.316

High

628362

ODR4
Protein odr-4 homolog

1

0

High-throughput

0.232

Low

628368

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

1

0

High-throughput

0.232

Low

628375

CDCA7
Cell division cycle-associated protein 7

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025