Interactor 1: Q7KJ08 (Q7KJ08)
receptor protein-tyrosine kinase (EC 2.7.10.1)
Gene: Alk
Interactor 2: Q7KNQ9 (Q7KNQ9)
Connector enhancer of KSR protein CNK (Connector enhancer of ksr, isoform A) (Connector enhancer of ksr, isoform B) (SD09985p)
Gene: cnk
Species: Drosophila melanogaster
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.621 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 29066538 |
| Identification Methods | two hybrid |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CRIC_ras_sig~PK_Tyr_Ser-Thr, PH~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SAM_1 |
| Common GO terms | GO:0007169 - cell surface receptor protein tyrosine kinase signaling pathway GO:0070374 - positive regulation of ERK1 and ERK2 cascade |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
