Interactor 1: FIG4 (Q92562)
Polyphosphoinositide phosphatase (EC 3.1.3.-) (EC 3.1.3.36) (EC 3.1.3.86) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase) (SAC domain-containing protein 3) (Serine-protein phosphatase FIG4) (EC 3.1.3.16)
Gene: FIG4

Interactor 2: FYV1 (Q9Y2I7)
1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase) (Serine-protein kinase PIKFYVE) (EC 2.7.11.1)
Gene: PIKFYVE

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 0.60 0.712

The method score is based on:

Property Details
Experiments 26186194, 28514442, 32583743, 33961781, 35271311
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000139 - Golgi membrane
GO:0006661 - phosphatidylinositol biosynthetic process
GO:0010008 - endosome membrane
GO:0031901 - early endosome membrane
GO:0031902 - late endosome membrane
and 2 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 907
Hs

1 2098
+ Hs
+ Sc
+ Zm

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Last updated: 15 Jul 2024