HitPredict

Interactor 1: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Interactor 2: PKHA6 (Q9Y2H5)
Pleckstrin homology domain-containing family A member 6 (PH domain-containing family A member 6) (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3)
Gene: PLEKHA6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 530 Hs			1 1048
+	Hs
		1269656 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		PKHA5_HUMAN (1-1012): 2.52e-108: 365: 29.73
+	Hs
		1154059 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		NIPBL_HUMAN (150-1025): 1.8e-90: 321: 11.81
+	Hs
		1153313 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		PKHA7_HUMAN (1-953): 1.72e-90: 315: 23.76
+	Hs
		369815 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		NIPBL_HUMAN (150-1025): 1.8e-90: 321: 11.81
+	Hs
		369813 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		PKHA7_HUMAN (1-953): 1.72e-90: 315: 23.76
+	Hs
		782571 HNF4A_HUMAN (94-502): 1.21e-107: 331: 23.30		NIPBL_HUMAN (150-1025): 1.8e-90: 321: 11.81
+	Hs
		377401 GCR_HUMAN (3-495): 1.12e-103: 330: 22.64		NIPBL_HUMAN (150-1025): 1.8e-90: 321: 11.81
+	Hs
		1167393 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		MPRIP_HUMAN (2-667): 4.03e-48: 188: 13.90
+	Hs
		369860 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		MPRIP_HUMAN (2-667): 4.03e-48: 188: 13.90
+	Hs
		1270066 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		PCLO_HUMAN (153-1032): 2.17e-10: 67.3: 9.42
+	Hs
		377563 GCR_HUMAN (3-495): 1.12e-103: 330: 22.64		CNKR1_HUMAN (28-374): 5.87e-45: 176: 14.68
+	Hs
		377684 GCR_HUMAN (3-495): 1.12e-103: 330: 22.64		PKHA4_HUMAN (7-356): 9.25e-41: 164: 26.52
+	Hs
		490117 COT1_HUMAN (83-502): 2.36e-106: 326: 23.88		PKHA4_HUMAN (7-356): 9.25e-41: 164: 26.52
+	Hs
		487522 ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59		NIPBL_HUMAN (150-1025): 1.8e-90: 321: 11.81
+	Hs
		487126 ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59		RASA1_HUMAN (76-636): 1.95e-46: 183: 12.80