HitPredict

Interactor 1: SNX27 (Q96L92)
Sorting nexin-27
Gene: SNX27

Interactor 2: KDIS (Q9ULH0)
Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein)
Gene: KIDINS220

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31541095, 34315543
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 541 Hs			1 1771
+	Dm
		677732 DLG1_DROME (44-160): 1.73e-12: 72.3: 19.49		Q9W2I0_DROME (1-1280): 0: 1136: 39.15
+	Hs
		1296957 SNX27_HUMAN (1-541): 0: 625: 100.00		ANR50_HUMAN (1-307): 2.84e-80: 295: 31.27
+	Hs
		166999 SNX27_HUMAN (1-541): 0: 625: 100.00		ANR28_HUMAN (411-503): 1.03e-09: 65.9: 6.45
+	Mm
		103604 NEB2_MOUSE (40-314): 1.09e-33: 138: 17.98		ANK3_MOUSE (206-542): 2.22e-68: 258: 19.04
+	Mm
		103600 SHAN3_MOUSE (44-148): 2.57e-21: 100: 36.19		ANK3_MOUSE (206-542): 2.22e-68: 258: 19.04
+	Mm
		1163989 NEB2_MOUSE (40-314): 1.09e-33: 138: 17.98		ANK2_MOUSE (3-228): 3.65e-52: 206: 25.22
+	Mm
		1116022 SHAN3_MOUSE (44-148): 2.57e-21: 100: 36.19		ANK2_MOUSE (3-228): 3.65e-52: 206: 25.22
+	Hs
		167037 NEB1_HUMAN (40-375): 2.86e-39: 155: 14.43		ANR28_HUMAN (411-503): 1.03e-09: 65.9: 6.45
+	Hs
		167005 NEB2_HUMAN (40-314): 3.95e-34: 139: 17.98		ANR28_HUMAN (411-503): 1.03e-09: 65.9: 6.45
+	Mm
		1115906 SHAN3_MOUSE (44-148): 2.57e-21: 100: 36.19		ANR28_MOUSE (411-503): 5.23e-10: 66.7: 6.45
+	Ce
		88217 D3YT29_CAEEL (32-299): 2.53e-11: 68.4: 15.13		ANKHM_CAEEL (21-356): 4.61e-18: 93.6: 26.89