HitPredict

Interactor 1: NCK (Q8IPW2)
SH2/SH3 adapter protein dreadlocks
Gene: dock

Interactor 2: PTP61 (Q9W0G1)
Tyrosine-protein phosphatase non-receptor type 61F (EC 3.1.3.48) (dPTP61F)
Gene: Ptp61F

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.833

The method score is based on:

Property Details
Experiments 14605208, 8663600, 38944040
Identification Methods two hybrid, coimmunoprecipitation, anti tag coimmunoprecipitation, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~Y_phosphatase
Common GO terms GO:0005829 - cytosol
GO:0007411 - axon guidance
GO:0019901 - protein kinase binding
GO:0046627 - negative regulation of insulin receptor signaling pathway
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 548
Dm

1 548
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Service provided by Combinatics, Japan

Last updated: 11Aug2025