HitPredict

Interactor 1: PK3CD (O00329)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) (PI3K-delta) (PI3Kdelta) (PtdIns-3-kinase subunit delta) (EC 2.7.1.137) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta) (PtdIns-3-kinase subunit p110-delta) (p110delta)
Gene: PIK3CD

Interactor 2: PK3CD (O00329)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) (PI3K-delta) (PI3Kdelta) (PtdIns-3-kinase subunit delta) (EC 2.7.1.137) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta) (PtdIns-3-kinase subunit p110-delta) (p110delta)
Gene: PIK3CD

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 9113989
Identification Methods in-gel kinase assay
Interaction Type phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains PI3_PI4_kinase~PI3_PI4_kinase, PI3K_C2~PI3_PI4_kinase, PI3K_rbd~PI3_PI4_kinase, PI3Ka~PI3_PI4_kinase, PI3K_C2~PI3Ka, PI3K_rbd~PI3K_rbd, PI3K_rbd~PI3Ka, PI3Ka~PI3Ka
Common GO terms GO:0001779 - natural killer cell differentiation
GO:0001819 - positive regulation of cytokine production
GO:0001938 - positive regulation of endothelial cell proliferation
GO:0002250 - adaptive immune response
GO:0002551 - mast cell chemotaxis
and 41 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 1044
Hs

1 1044
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Last updated: 11Aug2025