HitPredict

Interactor 1: LAMB2 (P55268)
Laminin subunit beta-2 (Laminin B1s chain) (Laminin-11 subunit beta) (Laminin-14 subunit beta) (Laminin-15 subunit beta) (Laminin-3 subunit beta) (Laminin-4 subunit beta) (Laminin-7 subunit beta) (Laminin-9 subunit beta) (S-laminin subunit beta) (S-LAM beta)
Gene: LAMB2

Interactor 2: PTPRK (Q15262)
Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48)
Gene: PTPRK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.80	0.705

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Laminin_EGF~fn3, Laminin_N~fn3
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1798 Hs			1 1439
+	Hs
		877415 LAMB2_HUMAN (1-1798): 0: 1052: 100.00		PTPRO_HUMAN (1162-1433): 5.11e-94: 333: 30.22
+	Hs
		433152 LAMB1_HUMAN (874-1798): 1.4e-42: 173: 14.84		PTPRK_HUMAN (26-1439): 0: 1191: 100.00
+	Hs
		172667 LAMA5_HUMAN (561-809): 2.08e-11: 71.9: 10.36		PTPRK_HUMAN (26-1439): 0: 1191: 100.00
+	Hs
		1069917 LAMA3_HUMAN (541-730): 8.16e-09: 63: 11.92		PTPRK_HUMAN (26-1439): 0: 1191: 100.00
+	Hs
		577015 NOTC2_HUMAN (295-686): 1.81e-25: 118: 13.07		PTPRA_HUMAN (668-1438): 0: 736: 30.62
+	Hs
		502836 LAMC1_HUMAN (892-1798): 4.14e-48: 192: 15.39		PTPRO_HUMAN (1162-1433): 5.11e-94: 333: 30.22
+	Hs
		433155 LAMB1_HUMAN (874-1798): 1.4e-42: 173: 14.84		PTPRO_HUMAN (1162-1433): 5.11e-94: 333: 30.22
+	Hs
		1271866 NET4_HUMAN (869-1058): 5.64e-14: 79.2: 23.29		NEO1_HUMAN (196-689): 3.76e-15: 83.6: 16.95
+	Hs
		317794 NET1_HUMAN (782-952): 7.93e-10: 65.7: 21.11		NEO1_HUMAN (196-689): 3.76e-15: 83.6: 16.95
+	Dm
		561760 NETB_DROME (1065-1190): 7.71e-11: 69.3: 29.73		PTP69_DROME (1-463): 1.18e-13: 78.5: 6.97