HitPredict

Interactor 1: PARD3 (Q8TEW0)
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)
Gene: PARD3

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding GO:0005886 - plasma membrane GO:0032266 - phosphatidylinositol-3-phosphate binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1356 Hs			1 779
+	Hs
		1353278 PARD3_HUMAN (1-1356): 0: 706: 100.00		PKHA1_HUMAN (3-261): 4.01e-41: 157: 17.49
+	Hs
		1353277 PARD3_HUMAN (1-1356): 0: 706: 100.00		PKHA5_HUMAN (114-732): 4.97e-38: 154: 17.22
+	Hs
		1213072 PARD3_HUMAN (1-1356): 0: 706: 100.00		RHG21_HUMAN (12-723): 2.27e-35: 147: 13.40
+	Hs
		1106492 PARD3_HUMAN (1-1356): 0: 706: 100.00		GAB1_HUMAN (52-668): 9.24e-36: 146: 10.87
+	Hs
		1234877 PARD3_HUMAN (1-1356): 0: 706: 100.00		PKHA7_HUMAN (153-638): 3.81e-34: 143: 23.37
+	Hs
		1353312 PARD3_HUMAN (1-1356): 0: 706: 100.00		FARP1_HUMAN (6-166): 1.24e-24: 112: 18.07
+	Hs
		1353309 PARD3_HUMAN (1-1356): 0: 706: 100.00		PKHA6_HUMAN (287-614): 3.87e-24: 111: 19.28
+	Hs
		1090182 PTN13_HUMAN (39-368): 1.89e-16: 87.8: 12.50		PKHA4_HUMAN (1-779): 1.18e-148: 455: 100.00
+	Mm
		999791 DLG3_MOUSE (571-1119): 2.89e-28: 125: 13.47		CNKR2_MOUSE (1-468): 6.67e-45: 176: 14.78
+	Mm
		1223600 DLG4_MOUSE (540-699): 7.92e-23: 107: 27.98		CNKR2_MOUSE (1-468): 6.67e-45: 176: 14.78
+	Mm
		1282975 DLG1_MOUSE (274-579): 3.14e-22: 106: 17.50		CNKR2_MOUSE (1-468): 6.67e-45: 176: 14.78
+	Rn
		723907 DLG4_RAT (540-699): 1.01e-22: 107: 27.98		CNKR2_RAT (1-468): 1.86e-44: 175: 14.59
+	Mm
		1282981 DLG2_MOUSE (155-396): 6.11e-22: 105: 16.41		CNKR2_MOUSE (1-468): 6.67e-45: 176: 14.78
+	Hs
		1368721 DLG3_HUMAN (556-1119): 1.07e-27: 123: 13.64		PKHA2_HUMAN (37-252): 6.2e-39: 151: 20.50
+	Hs
		299794 MPDZ_HUMAN (426-543): 5.29e-21: 102: 34.75		PKHA1_HUMAN (3-261): 4.01e-41: 157: 17.49
+	Hs
		1152420 DLG2_HUMAN (145-396): 1.52e-21: 103: 15.48		PKHA2_HUMAN (37-252): 6.2e-39: 151: 20.50
+	Hs
		299793 MPDZ_HUMAN (426-543): 5.29e-21: 102: 34.75		PKHA2_HUMAN (37-252): 6.2e-39: 151: 20.50
+	Hs
		1090185 PTN13_HUMAN (39-368): 1.89e-16: 87.8: 12.50		PKHA1_HUMAN (3-261): 4.01e-41: 157: 17.49
+	Hs
		1090184 PTN13_HUMAN (39-368): 1.89e-16: 87.8: 12.50		PKHA2_HUMAN (37-252): 6.2e-39: 151: 20.50
+	Hs
		1234914 MAGI1_HUMAN (413-780): 3.17e-16: 87: 15.48		PKHA7_HUMAN (153-638): 3.81e-34: 143: 23.37