Interactor 1: DI3L1 (Q8TF46)
DIS3-like exonuclease 1 (EC 3.1.13.1)
Gene: DIS3L

Interactor 2: EXOS4 (Q9NPD3)
Exosome complex component RRP41 (Exosome component 4) (Ribosomal RNA-processing protein 41) (p12A)
Gene: EXOSC4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.932

The method score is based on:

Property Details
Experiments 26496610, 24981860, 33961781, 20531386, unassigned3799
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains OB_Dis3~RNase_PH, OB_Dis3~RNase_PH_C, RNB~RNase_PH
Common GO terms GO:0000175 - 3'-5'-RNA exonuclease activity
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0003723 - RNA binding
GO:0005829 - cytosol
GO:0006396 - RNA processing
and 2 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1054
Hs

1 245
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Last updated: 11Aug2025