Protein: PLAK2
PALM2-AKAP2 fusion protein (A-kinase anchor protein 2) (AKAP-2) (AKAP-KL) (Paralemmin A kinase anchor protein) (Paralemmin-2) (Protein kinase A-anchoring protein 2) (PRKA2)

Gene: PLAK2, PALM2AKAP2
Organism: Homo sapiens
Interactions: 94
UniProt ID: Q9Y2D5

Gene Ontology (top 5):
GO:0008360 - regulation of cell shape
GO:0016324 - apical plasma membrane
GO:0098552 - side of membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

568838

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

5

1

Small-scale

0.656

High

498380

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

3

4

High-throughput

0.609

High

679413

KAP3
cAMP-dependent protein kinase type II-beta regulatory subunit

3

4

High-throughput

0.609

High

547287

EZRI
Ezrin

2

4

High-throughput

0.584

High

548766

VAV
Proto-oncogene vav

2

2

High-throughput

0.574

High

1021477

ANK3
Ankyrin-3

3

3

High-throughput

0.569

High

610799

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

2

1

High-throughput

0.558

High

965177

ANK2
Ankyrin-2

2

3

High-throughput

0.552

High

533887

KAP2
cAMP-dependent protein kinase type II-alpha regulatory subunit

2

4

Small-scale

0.550

High

725078

MYH9
Myosin-9

1

1

High-throughput

0.536

High

809489

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

1

High-throughput

0.536

High

892128

ACTB
Actin, cytoplasmic 1

2

2

High-throughput

0.533

High

1159754

RHGBA
Rho GTPase-activating protein 11A

2

1

High-throughput

0.521

High

1217537

FMNL3
Formin-like protein 3

1

0

High-throughput

0.513

High

598384

FLNA
Filamin-A

1

1

High-throughput

0.489

High

1085106

DREB
Drebrin

1

2

High-throughput

0.489

High

1232646

SYNPO
Synaptopodin

1

1

High-throughput

0.489

High

1268122

MY18A
Unconventional myosin-XVIIIa

1

3

High-throughput

0.489

High

1291829

CERS2
Ceramide synthase 2

1

1

High-throughput

0.489

High

1343818

ANLN
Anillin

1

1

High-throughput

0.489

High

1343918

MYO5C
Unconventional myosin-Vc

1

1

High-throughput

0.489

High

1344057

PDLI7
PDZ and LIM domain protein 7

1

1

High-throughput

0.489

High

719791

RADI
Radixin

1

3

High-throughput

0.479

High

802782

CRK
Adapter molecule crk

1

5

High-throughput

0.479

High

1169514

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

3

High-throughput

0.479

High

1287438

OPTN
Optineurin

1

5

High-throughput

0.470

High

182225

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

2

High-throughput

0.437

High

411895

LCK
Tyrosine-protein kinase Lck

1

3

High-throughput

0.437

High

522281

CADH1
Cadherin-1

1

1

High-throughput

0.437

High

523219

SRC
Proto-oncogene tyrosine-protein kinase Src

1

3

High-throughput

0.437

High

557836

NCK1
SH2/SH3 adapter protein NCK1

1

4

High-throughput

0.437

High

670289

MARCS
Myristoylated alanine-rich C-kinase substrate

1

1

High-throughput

0.437

High

840612

VASP
Vasodilator-stimulated phosphoprotein

1

1

High-throughput

0.437

High

915540

ACTA
Actin, aortic smooth muscle

1

2

High-throughput

0.437

High

924967

GRB2
Growth factor receptor-bound protein 2

1

6

High-throughput

0.437

High

930061

ACTG
Actin, cytoplasmic 2

1

2

High-throughput

0.437

High

1048392

SCRB2
Lysosome membrane protein 2

1

1

High-throughput

0.437

High

1080818

ZYX
Zyxin

1

1

High-throughput

0.437

High

1172330

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1286759

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.437

High

1292138

VMP1
Vacuole membrane protein 1

1

1

High-throughput

0.437

High

1315551

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

1

High-throughput

0.437

High

1318259

KPCD2
Serine/threonine-protein kinase D2

1

1

High-throughput

0.437

High

1330568

CHM4B
Charged multivesicular body protein 4b

1

1

High-throughput

0.437

High

1333822

ECT2
Protein ECT2

1

2

High-throughput

0.437

High

1355080

TES
Testin

1

1

High-throughput

0.437

High

882649

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

1

High-throughput

0.407

High

1032695

CTBP1
C-terminal-binding protein 1

1

1

High-throughput

0.407

High

1153465

PKHA7
Pleckstrin homology domain-containing family A member 7

1

2

High-throughput

0.407

High

1138026

SYDE2
Rho GTPase-activating protein SYDE2

2

0

High-throughput

0.298

High

129088

SYT5
Synaptotagmin-5

2

0

High-throughput

0.288

High

417105

KCRM
Creatine kinase M-type

2

0

High-throughput

0.288

High

985313

FOLC
Folylpolyglutamate synthase, mitochondrial

2

0

High-throughput

0.288

High

1217205

LACC1
Purine nucleoside phosphorylase LACC1

2

0

High-throughput

0.288

High

1245690

MSPD2
Motile sperm domain-containing protein 2

2

0

High-throughput

0.288

High

1350437

E2AK4
eIF-2-alpha kinase GCN2

2

0

High-throughput

0.288

High

1377189

AP3M1
AP-3 complex subunit mu-1

2

0

High-throughput

0.288

High

440811

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.279

Low

718339

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.279

Low

813216

CAZA2
F-actin-capping protein subunit alpha-2

1

0

High-throughput

0.279

Low

906642

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

0

High-throughput

0.279

Low

1355284

LIMA1
LIM domain and actin-binding protein 1

1

0

High-throughput

0.279

Low

637094

ATPA
ATP synthase subunit alpha, mitochondrial

1

0

High-throughput

0.269

Low

149442

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

198310

DC1L2
Cytoplasmic dynein 1 light intermediate chain 2

1

0

High-throughput

0.249

Low

229100

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.249

Low

348280

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.249

Low

352316

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

451610

CLCA
Clathrin light chain A

1

0

High-throughput

0.249

Low

502700

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.249

Low

557006

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

High-throughput

0.249

Low

566508

KPCA
Protein kinase C alpha type

1

0

High-throughput

0.249

Low

581084

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

0

High-throughput

0.249

Low

615876

GCSP
Glycine dehydrogenase

1

0

High-throughput

0.249

Low

655513

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

0

High-throughput

0.249

Low

669084

PML
Protein PML

1

0

High-throughput

0.249

Low

685122

STIP1
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.249

Low

1066901

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.249

Low

1200772

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.249

Low

1261451

NUDC2
NudC domain-containing protein 2

1

0

High-throughput

0.249

Low

1267278

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.249

Low

1296963

SNX27
Sorting nexin-27

1

0

High-throughput

0.249

Low

1309318

MEP50
Methylosome protein WDR77

1

0

High-throughput

0.249

Low

1328314

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.249

Low

1328916

ATG5
Autophagy protein 5

1

0

High-throughput

0.249

Low

1349902

LUZP4
Leucine zipper protein 4

1

0

Small-scale

0.249

Low

1354507

ZO2
Tight junction protein ZO-2

1

0

High-throughput

0.249

Low

1354910

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

1377152

FBW1A
F-box/WD repeat-containing protein 1A

1

0

High-throughput

0.249

Low

1377190

SCC4
MAU2 chromatid cohesion factor homolog

1

0

High-throughput

0.249

Low

309998

ATE1
Arginyl-tRNA--protein transferase 1

1

0

High-throughput

0.232

Low

484223

CALM3
Calmodulin-3

1

0

High-throughput

0.232

Low

1231949

GPD1L
Glycerol-3-phosphate dehydrogenase 1-like protein

1

0

High-throughput

0.232

Low

1272715

CSN5
COP9 signalosome complex subunit 5

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024