Interactor 1: CNKR2 (Q8WXI2)
Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR 2) (CNK homolog protein 2) (CNK2)
Gene: CNKSR2
Interactor 2: TNIK (Q9UKE5)
TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)
Gene: TNIK
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.58 | 1.00 | 0.762 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17043677, unassigned1973 |
| Identification Methods | two hybrid, two hybrid fragment pooling approach |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CRIC_ras_sig~Pkinase, PH~Pkinase, Pkinase~SAM_1 |
| Common GO terms | GO:0005737 - cytoplasm GO:0035556 - intracellular signal transduction GO:0070062 - extracellular exosome GO:0098978 - glutamatergic synapse |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025