Interactor 1: DRICE (O01382)
Caspase (EC 3.4.22.-) (drICE) [Cleaved into: Caspase subunit p21; Caspase subunit p12]
Gene: DRICE

Interactor 2: DIAP2 (Q24307)
Death-associated inhibitor of apoptosis 2 (Apoptosis 2 inhibitor) (IAP homolog A) (IAP-like protein) (ILP) (dILP) (Inhibitor of apoptosis 2)
Gene: DIAP2

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 1.00 0.806

The method score is based on:

Property Details
Experiments 16485033, 18166655
Identification Methods affinity chromatography technology, pull down, protease assay
Interaction Type physical association, protein cleavage

The annotation score is based on:

Property Details
Interacting Pfam domains BIR~Peptidase_C14
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006915 - apoptotic process
GO:0031625 - ubiquitin protein ligase binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 339
Dm

1 498
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024