HitPredict

Interactor 1: LZTS2 (Q9BRK4)
Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1)
Gene: LZTS2

Interactor 2: SI1L2 (Q9P2F8)
Signal-induced proliferation-associated 1-like protein 2 (SIPA1-like protein 2)
Gene: SIPA1L2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.50	0.633

Property	Details
Experiments	26186194, 28514442, 29395067, 33961781
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 669 Hs			1 1722
+	Hs
		1454568 LZTS1_HUMAN (26-653): 1.4e-35: 144: 34.75		SI1L2_HUMAN (1-1722): 0: 1768: 100.00
+	Hs
		175999 N4BP3_HUMAN (17-640): 2.91e-35: 142: 27.16		SI1L2_HUMAN (1-1722): 0: 1768: 100.00
+	Hs
		244902 LZTS3_HUMAN (1-669): 8.99e-32: 133: 31.33		SI1L2_HUMAN (1-1722): 0: 1768: 100.00
+	Hs
		1226303 CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52		SI1L2_HUMAN (1-1722): 0: 1768: 100.00
+	Hs
		208727 LZTS2_HUMAN (1-669): 3.78e-58: 209: 100.00		SI1L1_HUMAN (1-1719): 0: 1313: 47.69
+	Hs
		244604 LZTS2_HUMAN (1-669): 3.78e-58: 209: 100.00		SI1L3_HUMAN (15-1714): 0: 1262: 43.84
+	Hs
		208601 LZTS3_HUMAN (1-669): 8.99e-32: 133: 31.33		SI1L1_HUMAN (1-1719): 0: 1313: 47.69
+	Hs
		244515 LZTS3_HUMAN (1-669): 8.99e-32: 133: 31.33		SI1L3_HUMAN (15-1714): 0: 1262: 43.84
+	Hs
		208680 CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52		SI1L1_HUMAN (1-1719): 0: 1313: 47.69
+	Hs
		244542 MYH9_HUMAN (40-669): 1.08e-16: 86.6: 10.13		SI1L3_HUMAN (15-1714): 0: 1262: 43.84
+	Hs
		244596 MY18A_HUMAN (320-525): 1.14e-09: 64: 19.46		SI1L3_HUMAN (15-1714): 0: 1262: 43.84
+	Hs
		244583 CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52		SI1L3_HUMAN (15-1714): 0: 1262: 43.84
+	Hs
		890853 PHLB1_HUMAN (8-631): 1.93e-26: 117: 14.83		TSC2_HUMAN (538-860): 2.26e-106: 379: 21.07
+	Hs
		1135341 SLMAP_HUMAN (327-641): 2.81e-23: 107: 19.59		RGPA1_HUMAN (504-833): 2.58e-96: 348: 22.99
+	Hs
		157445 CTRO_HUMAN (295-638): 1.1e-11: 70.4: 17.03		RGPA2_HUMAN (502-852): 6.79e-103: 368: 21.63
+	Hs
		1081697 CGNL1_HUMAN (326-667): 1.66e-10: 66.7: 15.80		RGPA2_HUMAN (502-852): 6.79e-103: 368: 21.63
+	Hs
		1390851 LZTS2_HUMAN (1-669): 3.78e-58: 209: 100.00		SIPA1_HUMAN (1396-1707): 6.1e-20: 99.4: 17.57
+	Hs
		772955 MYH9_HUMAN (40-669): 1.08e-16: 86.6: 10.13		SIPA1_HUMAN (1396-1707): 6.1e-20: 99.4: 17.57
+	Hs
		1143196 PLEC_HUMAN (327-659): 1.62e-09: 63.5: 20.77		KMT2C_HUMAN (1166-1660): 1.85e-11: 71.9: 9.11
+	Hs
		158047 CTRO_HUMAN (295-638): 1.1e-11: 70.4: 17.03		PCLO_HUMAN (993-1718): 3.76e-09: 64.3: 9.71