HitPredict

Interactor 1: ADA33 (Q9BZ11)
Disintegrin and metalloproteinase domain-containing protein 33 (ADAM 33) (EC 3.4.24.-)
Gene: ADAM33

Interactor 2: LRP12 (Q9Y561)
Low-density lipoprotein receptor-related protein 12 (LDLR-related protein 12) (LRP-12) (Suppressor of tumorigenicity 7 protein)
Gene: LRP12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 813 Hs			1 859
+	Hs
		1105795 ADAM9_HUMAN (1-787): 1.9e-177: 532: 31.45		ST14_HUMAN (61-457): 1.83e-37: 153: 17.63
+	Hs
		274913 ADA33_HUMAN (1-813): 0: 569: 100.00		LRP5_HUMAN (162-255): 4.05e-14: 79: 43.75
+	Hs
		287605 ADA33_HUMAN (1-813): 0: 569: 100.00		LRP6_HUMAN (394-488): 7.1e-09: 62: 32.32
+	Hs
		1461076 ADA30_HUMAN (48-750): 3.21e-131: 411: 29.11		ST14_HUMAN (61-457): 1.83e-37: 153: 17.63
+	Hs
		1459974 ATS1_HUMAN (36-668): 3.06e-110: 361: 19.52		ST14_HUMAN (61-457): 1.83e-37: 153: 17.63
+	Hs
		1352115 ATS15_HUMAN (15-668): 2.03e-107: 353: 18.75		ST14_HUMAN (61-457): 1.83e-37: 153: 17.63
+	Hs
		1278335 ADA21_HUMAN (22-747): 6.48e-141: 435: 27.97		LRP10_HUMAN (1-297): 3.52e-10: 65.7: 15.87
+	Hs
		273736 ATS4_HUMAN (37-668): 2.23e-130: 411: 19.59		LRP5_HUMAN (162-255): 4.05e-14: 79: 43.75
+	Hs
		274932 ADA30_HUMAN (48-750): 3.21e-131: 411: 29.11		LRP5_HUMAN (162-255): 4.05e-14: 79: 43.75
+	Hs
		273737 ATS4_HUMAN (37-668): 2.23e-130: 411: 19.59		LRP6_HUMAN (394-488): 7.1e-09: 62: 32.32
+	Hs
		287629 ADA30_HUMAN (48-750): 3.21e-131: 411: 29.11		LRP6_HUMAN (394-488): 7.1e-09: 62: 32.32
+	Hs
		270597 ATS1_HUMAN (36-668): 3.06e-110: 361: 19.52		LRP4_HUMAN (2-246): 2.38e-14: 80: 9.41
+	Hs
		562768 ATS1_HUMAN (36-668): 3.06e-110: 361: 19.52		BMP1_HUMAN (254-401): 7.75e-10: 64.9: 26.00
+	Hs
		161111 ADA10_HUMAN (196-519): 4.31e-23: 107: 27.63		ST14_HUMAN (61-457): 1.83e-37: 153: 17.63
+	Hs
		161098 ADA10_HUMAN (196-519): 4.31e-23: 107: 27.63		TEN3_HUMAN (2-247): 2.22e-23: 109: 10.44
+	Dm
		262958 Q9VAI2_DROME (336-519): 2.14e-20: 99.4: 33.67		TENM_DROME (3-276): 2.18e-20: 99.6: 11.96
+	Dm
		1478787 Q9VJW9_DROME (298-519): 2.01e-17: 89.4: 29.30		TENA_DROME (3-276): 3.46e-22: 105: 12.10
+	Dm
		263067 Q9VJW9_DROME (298-519): 2.01e-17: 89.4: 29.30		TENM_DROME (3-276): 2.18e-20: 99.6: 11.96
+	Dm
		1478806 Q9VJW9_DROME (298-519): 2.01e-17: 89.4: 29.30		Q9W4Y4_DROME (1-257): 1.99e-10: 67.3: 20.27