Interactor 1: CASPA (Q9I9L7)
Caspase a (EC 3.4.22.36) [Cleaved into: Caspase a subunit p20; Caspase a subunit p10]
Gene: CASPA
Interactor 2: ASC (Q9I9N6)
Apoptosis-associated speck-like protein containing a CARD (PYD and CARD domain-containing protein)
Gene: pycard
Species: Danio rerio
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12464617 |
| Identification Methods | anti tag coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PYRIN~PYRIN |
| Common GO terms | GO:0002221 - pattern recognition receptor signaling pathway GO:0005737 - cytoplasm GO:0032090 - Pyrin domain binding GO:0032731 - positive regulation of interleukin-1 beta production GO:0045087 - innate immune response and 3 others more... |
| Homologous interactions | 13 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
