HitPredict

Interactor 1: EXOS5 (Q9LX74)
Exosome complex exonuclease RRP46 homolog (EC 3.1.13.-) (Exosome component 5) (Ribosomal RNA-processing protein 46)
Gene: RRP46

Interactor 2: RRP4 (Q9ZVT7)
Exosome complex component RRP4 homolog (Ribosomal RNA-processing protein 4) (AtRRP4) (AtRrp4p)
Gene: RRP4

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	18160042
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	RNase_PH~RRP4_S1
Common GO terms	GO:0000178 - exosome (RNase complex) GO:0005730 - nucleolus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 239 At			1 322
+	At
		1456928 RRP41_ARATH (2-237): 4.91e-68: 211: 21.86		RRP4_ARATH (1-322): 6.41e-163: 458: 100.00
+	At
		60912 RP41L_ARATH (1-238): 6.49e-63: 198: 23.05		RRP4_ARATH (1-322): 6.41e-163: 458: 100.00
+	Hs
		1118340 EXOS4_HUMAN (2-238): 1.11e-67: 210: 21.37		EXOS2_HUMAN (26-315): 3.95e-107: 315: 38.14
+	Sp
		206877 RRP41_SCHPO (1-222): 3.6e-61: 193: 25.00		RRP4_SCHPO (39-289): 2.86e-112: 330: 41.83
+	Dm
		1479003 Q9VK19_DROME (2-239): 5.6e-69: 213: 22.95		Q9W1M9_DROME (30-317): 5.31e-101: 300: 35.42
+	Sc
		804722 RRP41_YEAST (2-238): 5.74e-54: 175: 22.89		RRP4_YEAST (29-293): 3.87e-109: 323: 34.38
+	Hs
		1118314 EXOS8_HUMAN (2-233): 2.44e-54: 177: 13.33		EXOS2_HUMAN (26-315): 3.95e-107: 315: 38.14
+	Hs
		1118343 EXOS5_HUMAN (14-238): 2.09e-52: 171: 39.11		EXOS2_HUMAN (26-315): 3.95e-107: 315: 38.14
+	Sp
		268495 RRP45_SCHPO (3-238): 2.07e-45: 154: 13.77		RRP4_SCHPO (39-289): 2.86e-112: 330: 41.83
+	Sp
		206903 RRP46_SCHPO (20-238): 1.91e-45: 152: 23.64		RRP4_SCHPO (39-289): 2.86e-112: 330: 41.83
+	Sc
		804730 RRP46_YEAST (17-238): 2.85e-43: 147: 22.61		RRP4_YEAST (29-293): 3.87e-109: 323: 34.38
+	Dm
		1475400 Q9VGZ2_DROME (10-238): 1.22e-50: 166: 25.33		Q9W1M9_DROME (30-317): 5.31e-101: 300: 35.42
+	Hs
		1118279 EXOS7_HUMAN (2-236): 5.63e-43: 148: 15.88		EXOS2_HUMAN (26-315): 3.95e-107: 315: 38.14
+	Dm
		1487618 Q9VW53_DROME (9-237): 3.66e-45: 155: 21.25		Q9W1M9_DROME (30-317): 5.31e-101: 300: 35.42
+	Dm
		1345980 Q8T4A9_DROME (2-235): 5.7e-44: 154: 20.15		Q9W1M9_DROME (30-317): 5.31e-101: 300: 35.42
+	Sp
		1068455 MTR3_SCHPO (9-172): 5.43e-33: 121: 21.14		RRP4_SCHPO (39-289): 2.86e-112: 330: 41.83
+	Tb
		1378796 Q95Z13_9TRYP (3-234): 1.25e-47: 159: 19.34		Q95Z16_9TRYP (48-289): 4e-94: 283: 37.89
+	Tb
		1378792 Q95Z09_9TRYP (5-230): 1.6e-45: 154: 23.70		Q95Z16_9TRYP (48-289): 4e-94: 283: 37.89
+	Dm
		1177511 Q29QQ9_DROME (5-239): 1.43e-34: 127: 18.41		Q9W1M9_DROME (30-317): 5.31e-101: 300: 35.42
+	Tb
		1302649 Q8IEW0_9TRYP (3-209): 1.29e-39: 138: 19.82		Q95Z16_9TRYP (48-289): 4e-94: 283: 37.89