HitPredict

Interactor 1: RRP41 (Q9SP08)
Exosome complex component RRP41 homolog (Ribosomal RNA-processing protein 41) (AtRRP41) (AtRrp41p)
Gene: RRP41

Interactor 2: RRP4 (Q9ZVT7)
Exosome complex component RRP4 homolog (Ribosomal RNA-processing protein 4) (AtRRP4) (AtRrp4p)
Gene: RRP4

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	25144737, 11809881, 18160042
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	RNase_PH~RRP4_S1
Common GO terms	GO:0000178 - exosome (RNase complex) GO:0003723 - RNA binding GO:0005730 - nucleolus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 241 At			1 322
+	At
		60912 RP41L_ARATH (10-233): 1.15e-68: 213: 28.57		RRP4_ARATH (1-322): 6.41e-163: 458: 100.00
+	At
		1444336 CER7_ARATH (1-240): 8.32e-53: 178: 15.83		RRP4_ARATH (1-322): 6.41e-163: 458: 100.00
+	At
		1443597 EXOS5_ARATH (10-236): 4.66e-54: 175: 23.67		RRP4_ARATH (1-322): 6.41e-163: 458: 100.00
+	Hs
		1118340 EXOS4_HUMAN (1-236): 1.32e-80: 243: 47.68		EXOS2_HUMAN (26-315): 3.95e-107: 315: 38.14
+	Sp
		206877 RRP41_SCHPO (1-235): 7.36e-70: 215: 39.83		RRP4_SCHPO (39-289): 2.86e-112: 330: 41.83
+	Dm
		1479003 Q9VK19_DROME (1-232): 1.83e-74: 227: 40.60		Q9W1M9_DROME (30-317): 5.31e-101: 300: 35.42
+	Sc
		804722 RRP41_YEAST (1-241): 6.85e-63: 198: 35.66		RRP4_YEAST (29-293): 3.87e-109: 323: 34.38
+	Hs
		1118314 EXOS8_HUMAN (1-234): 3.64e-59: 189: 19.85		EXOS2_HUMAN (26-315): 3.95e-107: 315: 38.14
+	Sp
		268495 RRP45_SCHPO (5-238): 2.85e-49: 165: 13.06		RRP4_SCHPO (39-289): 2.86e-112: 330: 41.83
+	Sp
		1068455 MTR3_SCHPO (14-236): 1.85e-44: 151: 26.20		RRP4_SCHPO (39-289): 2.86e-112: 330: 41.83
+	Hs
		1118279 EXOS7_HUMAN (5-233): 7.27e-50: 166: 15.04		EXOS2_HUMAN (26-315): 3.95e-107: 315: 38.14
+	Hs
		1118343 EXOS5_HUMAN (2-234): 4.78e-50: 165: 25.11		EXOS2_HUMAN (26-315): 3.95e-107: 315: 38.14
+	Sp
		206903 RRP46_SCHPO (25-234): 3.58e-42: 144: 23.50		RRP4_SCHPO (39-289): 2.86e-112: 330: 41.83
+	Dm
		1345980 Q8T4A9_DROME (1-237): 6.71e-51: 172: 19.49		Q9W1M9_DROME (30-317): 5.31e-101: 300: 35.42
+	Hs
		1118285 EXOS6_HUMAN (3-228): 7.86e-46: 155: 28.75		EXOS2_HUMAN (26-315): 3.95e-107: 315: 38.14
+	Dm
		1487618 Q9VW53_DROME (14-234): 5.94e-49: 165: 23.97		Q9W1M9_DROME (30-317): 5.31e-101: 300: 35.42
+	Tb
		1378796 Q95Z13_9TRYP (2-237): 1.06e-55: 180: 31.09		Q95Z16_9TRYP (48-289): 4e-94: 283: 37.89
+	Dm
		1475400 Q9VGZ2_DROME (17-230): 8.93e-47: 156: 23.26		Q9W1M9_DROME (30-317): 5.31e-101: 300: 35.42
+	Dm
		1177511 Q29QQ9_DROME (5-239): 2.14e-44: 152: 16.79		Q9W1M9_DROME (30-317): 5.31e-101: 300: 35.42
+	Tb
		1302649 Q8IEW0_9TRYP (10-230): 1.78e-43: 148: 20.98		Q95Z16_9TRYP (48-289): 4e-94: 283: 37.89