HitPredict

Interactor 1: ORP3A (Q9LZM1)
Oxysterol-binding protein-related protein 3A (OSBP-related protein 3A) (Protein UNFERTILIZED EMBRYO SAC 18)
Gene: ORP3A

Interactor 2: VAP12 (Q9SHC8)
Vesicle-associated protein 1-2 (Plant VAP homolog 12) (AtPVA12) (VAMP-associated protein 1-2) [Cleaved into: Vesicle-associated protein 1-2, N-terminally processed]
Gene: PVA12

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.578

Property	Details
Experiments	19207211
Identification Methods	pull down, fluorescent resonance energy transfer, bimolecular fluorescence complementation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 453 At			1 239
+	At
		1354797 ORP2A_ARATH (2-438): 1.74e-164: 482: 29.46		VAP11_ARATH (2-239): 6.4e-93: 275: 81.51
+	Hs
		1419841 OSBL6_HUMAN (15-428): 7.03e-158: 472: 30.64		VAPA_HUMAN (3-238): 1.98e-65: 205: 23.89
+	Hs
		1431181 OSBL2_HUMAN (5-438): 3.8e-162: 467: 28.03		VAPA_HUMAN (3-238): 1.98e-65: 205: 23.89
+	Rn
		1317436 OSBL1_RAT (3-438): 5.28e-157: 470: 27.87		VAPA_RAT (3-233): 2.33e-63: 199: 25.20
+	Hs
		1417433 OSBL1_HUMAN (3-438): 1.33e-154: 464: 27.66		VAPA_HUMAN (3-238): 1.98e-65: 205: 23.89
+	Hs
		1433831 OSBL3_HUMAN (26-433): 7.35e-155: 462: 29.45		VAPA_HUMAN (3-238): 1.98e-65: 205: 23.89
+	Hs
		1380935 OSBP2_HUMAN (7-438): 4.19e-153: 459: 23.26		VAPA_HUMAN (3-238): 1.98e-65: 205: 23.89
+	Hs
		333179 OSBL6_HUMAN (15-428): 7.03e-158: 472: 30.64		VAPB_HUMAN (3-238): 9.16e-59: 187: 24.10
+	Hs
		1419831 OSBL7_HUMAN (53-428): 5.09e-151: 451: 31.85		VAPA_HUMAN (3-238): 1.98e-65: 205: 23.89
+	Hs
		1200615 OSBL2_HUMAN (5-438): 3.8e-162: 467: 28.03		Q53XM7_HUMAN (3-238): 9.16e-59: 187: 24.10
+	Hs
		333190 OSBL2_HUMAN (5-438): 3.8e-162: 467: 28.03		VAPB_HUMAN (3-238): 9.16e-59: 187: 24.10
+	Hs
		333172 OSBL1_HUMAN (3-438): 1.33e-154: 464: 27.66		VAPB_HUMAN (3-238): 9.16e-59: 187: 24.10
+	Hs
		333201 OSBL3_HUMAN (26-433): 7.35e-155: 462: 29.45		VAPB_HUMAN (3-238): 9.16e-59: 187: 24.10
+	Hs
		333127 OSBP2_HUMAN (7-438): 4.19e-153: 459: 23.26		VAPB_HUMAN (3-238): 9.16e-59: 187: 24.10
+	Hs
		332867 OSBP1_HUMAN (1-438): 4.36e-143: 430: 27.90		VAPB_HUMAN (3-238): 9.16e-59: 187: 24.10
+	Hs
		1340237 OSBL1_HUMAN (3-438): 1.33e-154: 464: 27.66		MSPD2_HUMAN (3-130): 8.73e-32: 123: 29.01
+	Sc
		818217 OSH2_YEAST (47-438): 3.92e-145: 447: 31.34		SCS2_YEAST (6-195): 1.95e-40: 140: 27.32
+	Sc
		777233 OSH1_YEAST (2-438): 2.43e-143: 440: 29.09		SCS2_YEAST (6-195): 1.95e-40: 140: 27.32
+	Sc
		1084936 OSH2_YEAST (47-438): 3.92e-145: 447: 31.34		SCS22_YEAST (6-172): 6.12e-38: 132: 28.09
+	Hs
		643380 OSBP1_HUMAN (1-438): 4.36e-143: 430: 27.90		MSPD2_HUMAN (3-130): 8.73e-32: 123: 29.01