Interactor 1: DRICE (O01382)
Caspase drICE (EC 3.4.22.-) (Death related ICE-like caspase) [Cleaved into: Caspase subunit p21; Caspase subunit p12]
Gene: DRICE
Interactor 2: CASP1 (O02002)
Caspase-1 (EC 3.4.22.-) [Cleaved into: Caspase-1 subunit p22; Caspase-1 subunit p13]
Gene: Dcp-1
Species: Drosophila melanogaster
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.67 | 1.00 | 0.820 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24862573, 28806103, unassigned4 |
| Identification Methods | enzymatic study, experimental interaction detection |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Peptidase_C14~Peptidase_C14 |
| Common GO terms | GO:0004197 - cysteine-type endopeptidase activity GO:0005737 - cytoplasm GO:0006508 - proteolysis GO:0006915 - apoptotic process GO:0010623 - programmed cell death involved in cell development and 7 others more... |
| Homologous interactions | 19 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
