HitPredict

Interactor 1: ABI3 (Q9P2A4)
ABI gene family member 3 (New molecule including SH3) (Nesh)
Gene: ABI3

Interactor 2: WASF3 (Q9UPY6)
Actin-binding protein WASF3 (Protein WAVE-3) (Verprolin homology domain-containing protein 3) (Wiskott-Aldrich syndrome protein family member 3) (WASP family protein member 3)
Gene: WASF3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030027 - lamellipodium GO:0030036 - actin cytoskeleton organization GO:0031209 - SCAR complex GO:0098885 - modification of postsynaptic actin cytoskeleton GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 366 Hs			1 502
+	Hs
		1364468 ABI3_HUMAN (1-366): 5.41e-88: 271: 100.00		WASF1_HUMAN (1-500): 3.44e-59: 206: 43.57
+	Hs
		1454450 ABI3_HUMAN (1-366): 5.41e-88: 271: 100.00		WASF2_HUMAN (1-484): 2.02e-57: 200: 43.60
+	Mm
		1296529 ABI1_MOUSE (1-314): 3.09e-64: 213: 34.35		WASF2_MOUSE (1-484): 9.93e-66: 222: 42.56
+	Rn
		1203409 ABI1_RAT (1-314): 1.01e-66: 219: 34.88		WASF1_RAT (1-500): 1.88e-56: 199: 43.04
+	Hs
		1124774 SRC8_HUMAN (40-363): 4.99e-43: 158: 16.12		WASF2_HUMAN (1-484): 2.02e-57: 200: 43.60
+	Hs
		1452526 ABI2_HUMAN (109-363): 1.97e-25: 108: 23.18		WASF3_HUMAN (1-502): 1.2e-73: 243: 100.00
+	Hs
		1364464 ABI2_HUMAN (109-363): 1.97e-25: 108: 23.18		WASF1_HUMAN (1-500): 3.44e-59: 206: 43.57
+	Hs
		215960 PACN2_HUMAN (17-363): 4.81e-45: 162: 14.29		SYNJ1_HUMAN (11-499): 4.08e-38: 151: 11.82
+	Hs
		215920 MYO1E_HUMAN (34-363): 9.99e-43: 160: 18.34		SYNJ1_HUMAN (11-499): 4.08e-38: 151: 11.82
+	Hs
		1452538 ABI2_HUMAN (109-363): 1.97e-25: 108: 23.18		WASF2_HUMAN (1-484): 2.02e-57: 200: 43.60
+	Hs
		1316686 ABI1_HUMAN (124-363): 6.4e-21: 95.9: 24.49		WASF1_HUMAN (1-500): 3.44e-59: 206: 43.57
+	Hs
		215948 PACN1_HUMAN (11-363): 1.32e-37: 142: 12.67		SYNJ1_HUMAN (11-499): 4.08e-38: 151: 11.82
+	Dm
		99175 DBNL_DROME (17-363): 3.49e-33: 131: 15.05		F2FB81_DROME (1-209): 1.44e-42: 162: 54.55
+	Mm
		92772 SH3G2_MOUSE (265-363): 3.48e-27: 111: 24.75		D3Z656_MOUSE (11-499): 2.19e-48: 181: 12.48
+	Rn
		204410 SH3G2_RAT (265-363): 2.51e-26: 109: 23.76		SYNJ1_RAT (11-480): 2.47e-43: 166: 12.19
+	Hs
		1091700 MYO1E_HUMAN (34-363): 9.99e-43: 160: 18.34		CBP_HUMAN (153-498): 1.19e-22: 104: 13.84
+	Hs
		215946 SH3G2_HUMAN (265-363): 7.93e-26: 108: 23.76		SYNJ1_HUMAN (11-499): 4.08e-38: 151: 11.82
+	Dd
		1200684 ABIA_DICDI (3-321): 7.75e-30: 119: 19.32		SCAR_DICDI (23-501): 1.21e-28: 119: 22.04
+	Hs
		571698 HCLS1_HUMAN (20-363): 4.03e-37: 141: 13.98		PCLO_HUMAN (91-484): 2.49e-10: 65.5: 14.18
+	Sp
		206133 MYO1_SCHPO (28-364): 4.89e-37: 144: 16.19		YFHH_SCHPO (254-438): 5.45e-09: 61.1: 18.72