Interactor 1: HECD1 (Q9ULT8)
E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1)
Gene: HECTD1

Interactor 2: HECD1 (Q9ULT8)
E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1)
Gene: HECTD1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.885

The method score is based on:

Property Details
Experiments 26949039, 28425671, 33853758, 35915203
Identification Methods enzymatic study, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~Ank_2, Ank_2~HECT, HECT~HECT, MIB_HERC2~MIB_HERC2, Sad1_UNC~Sad1_UNC
Common GO terms GO:0003170 - heart valve development
GO:0003281 - ventricular septum development
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0016567 - protein ubiquitination
GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process
and 3 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 2610
Hs

1 2610
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Last updated: 11Aug2025