HitPredict

Interactor 1: Q9VBY7 (Q9VBY7)
Protein lin-7 homolog
Gene: veli

Interactor 2: Q9VIJ4 (Q9VIJ4)
FI01467p (Varicose, isoform D)
Gene: vari

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	L27~L27, Guanylate_kin~PDZ, PDZ~PDZ
Common GO terms	GO:0005911 - cell-cell junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 195 Dm			1 615
+	Dm
		1269106 Q9VBY7_DROME (1-195): 6.68e-53: 169: 100.00		Q7KT16_DROME (1-615): 0: 543: 96.23
+	Hs
		1122734 LIN7C_HUMAN (1-195): 6.8e-53: 169: 80.00		MPP2_HUMAN (20-615): 1.62e-159: 471: 35.80
+	Dm
		122386 Q9VBY7_DROME (1-195): 6.68e-53: 169: 100.00		M9PJD0_DROME (18-615): 1.91e-143: 459: 23.56
+	Hs
		1450016 LIN7C_HUMAN (1-195): 6.8e-53: 169: 80.00		PALS2_HUMAN (29-615): 1.4e-154: 457: 37.90
+	Hs
		168758 LIN7C_HUMAN (1-195): 6.8e-53: 169: 80.00		CSKP_HUMAN (14-615): 2.39e-148: 453: 30.67
+	Mm
		267260 LIN7C_MOUSE (1-195): 6.8e-53: 169: 80.00		CSKP_MOUSE (14-615): 3.74e-148: 453: 30.67
+	Hs
		168750 LIN7B_HUMAN (1-195): 7.6e-52: 167: 77.44		CSKP_HUMAN (14-615): 2.39e-148: 453: 30.67
+	Mm
		267259 LIN7B_MOUSE (1-195): 5.31e-52: 167: 77.95		CSKP_MOUSE (14-615): 3.74e-148: 453: 30.67
+	Dm
		1172961 Q9VBY7_DROME (1-195): 6.68e-53: 169: 100.00		CSKP_DROME (27-615): 4.69e-147: 449: 30.90
+	Hs
		1212215 LIN7C_HUMAN (1-195): 6.8e-53: 169: 80.00		MPP7_HUMAN (19-615): 1.97e-140: 422: 28.62
+	Hs
		1325321 LIN7C_HUMAN (1-195): 6.8e-53: 169: 80.00		PALS1_HUMAN (45-614): 2.22e-135: 412: 28.01
+	Mm
		313209 LIN7C_MOUSE (1-195): 6.8e-53: 169: 80.00		PALS1_MOUSE (45-614): 4.96e-135: 411: 28.01
+	Dm
		54269 Q9VBY7_DROME (1-195): 6.68e-53: 169: 100.00		A1Z8G0_DROME (17-614): 7.71e-135: 408: 26.80
+	Dm
		1346103 Q9VBY7_DROME (1-195): 6.68e-53: 169: 100.00		Q8T5S9_DROME (17-614): 1.33e-133: 403: 27.11
+	Hs
		1103525 LIN7C_HUMAN (1-195): 6.8e-53: 169: 80.00		MPP3_HUMAN (23-614): 1.56e-130: 397: 27.14
+	Hs
		1006110 LIN7C_HUMAN (1-195): 6.8e-53: 169: 80.00		DLG4_HUMAN (163-286): 1.16e-16: 85.8: 17.56
+	Rn
		723908 LIN7B_RAT (1-195): 8.38e-52: 167: 77.95		DLG4_RAT (163-286): 1.04e-16: 85.8: 17.56
+	Hs
		1091580 LIN7C_HUMAN (1-195): 6.8e-53: 169: 80.00		DLG1_HUMAN (165-296): 1.92e-15: 81.9: 17.27
+	Mm
		313202 LIN7C_MOUSE (1-195): 6.8e-53: 169: 80.00		DLG1_MOUSE (165-296): 2.55e-15: 81.6: 16.55
+	Dm
		723806 Q9VBY7_DROME (1-195): 6.68e-53: 169: 100.00		DLG1_DROME (156-252): 3.8e-12: 71.5: 11.93