HitPredict

Interactor 1: NDC80 (O14777)
Kinetochore protein NDC80 homolog (Highly expressed in cancer protein) (Kinetochore protein Hec1) (HsHec1) (Kinetochore-associated protein 2) (Retinoblastoma-associated protein HEC)
Gene: NDC80

Interactor 2: BICD2 (Q8TD16)
Protein bicaudal D homolog 2 (Bic-D 2)
Gene: BICD2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	28718761, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 642 Hs			1 824
+	Hs
		155102 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		CP250_HUMAN (90-822): 4.68e-22: 104: 12.35
+	Mm
		1206614 TGO1_MOUSE (179-642): 3.73e-31: 132: 15.37		BICD1_MOUSE (11-813): 3.15e-54: 203: 60.98
+	Hs
		155149 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		EP15R_HUMAN (51-228): 1.55e-10: 66.8: 19.78
+	Hs
		725002 UACA_HUMAN (191-641): 1.51e-30: 130: 13.88		MYH9_HUMAN (530-824): 4.55e-10: 65.9: 12.75
+	Hs
		724994 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		CP250_HUMAN (90-822): 4.68e-22: 104: 12.35
+	Rn
		222472 MRCKA_RAT (181-627): 1.66e-21: 102: 10.82		MRCKA_RAT (16-623): 3.9e-11: 69.2: 16.43
+	Hs
		1268126 MRCKB_HUMAN (258-642): 1.73e-21: 102: 12.78		MY18A_HUMAN (6-719): 7.73e-11: 68.4: 17.85
+	Rn
		222476 MRCKB_RAT (266-642): 2.4e-19: 95.2: 10.61		MRCKA_RAT (16-623): 3.9e-11: 69.2: 16.43
+	Hs
		1137917 MRCKA_HUMAN (140-627): 3.84e-19: 94.5: 11.42		MRCKB_HUMAN (53-624): 1.17e-10: 67.6: 14.99
+	Hs
		724943 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		MY18A_HUMAN (6-719): 7.73e-11: 68.4: 17.85
+	Hs
		148460 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		CTRO_HUMAN (17-823): 1.27e-10: 67.6: 15.51
+	Hs
		724687 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		MYH10_HUMAN (530-823): 2.54e-10: 66.7: 11.45
+	Hs
		724686 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		MYH9_HUMAN (530-824): 4.55e-10: 65.9: 12.75
+	Hs
		148466 MYH11_HUMAN (180-641): 3.92e-16: 84.8: 12.24		CTRO_HUMAN (17-823): 1.27e-10: 67.6: 15.51
+	Hs
		725097 MYH11_HUMAN (180-641): 3.92e-16: 84.8: 12.24		MYH10_HUMAN (530-823): 2.54e-10: 66.7: 11.45
+	Hs
		148461 MYH10_HUMAN (171-636): 1.34e-15: 83.3: 12.84		CTRO_HUMAN (17-823): 1.27e-10: 67.6: 15.51
+	Hs
		725095 MYH10_HUMAN (171-636): 1.34e-15: 83.3: 12.84		MYH10_HUMAN (530-823): 2.54e-10: 66.7: 11.45
+	Mm
		93570 DESP_MOUSE (190-642): 1.18e-15: 83.5: 15.27		MYH9_MOUSE (530-824): 2.13e-09: 63.6: 12.75