Interactor 1: SOCS2 (O88582)
Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2)
Gene: SOCS2
Interactor 2: SOCS3 (O88583)
Suppressor of cytokine signaling 3 (SOCS-3) (Cytokine-inducible SH2 protein 3)
Gene: SOCS3
Species: Rattus norvegicus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16956890 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | SH2~SH2, SH2~SOCS_box |
| Common GO terms | GO:0005126 - cytokine receptor binding GO:0007259 - cell surface receptor signaling pathway via JAK-STAT GO:0009968 - negative regulation of signal transduction GO:0016567 - protein ubiquitination GO:0019221 - cytokine-mediated signaling pathway and 4 others more... |
| Homologous interactions | 19 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
